The secretory Rab GTPases, involving Rab26, Rab37, Rab3A/B/C/D, and Rab27A/B, are reported to be fundamental for regulated vesicle exocytosis.
Rab GTPases that regulate exocytosis (e.g., Rab27A and Rab37) could also be crucial for cancer progression [13,31].
asinina fall into a wide range of functional categories, including biological regulation, cell proliferation, and metabolic process, and include genes encoding Phe-Met-Arg-Phe-[NH.sub.2] (or, FMRF-amide), myomodulin, CDC123, RAB37, and dermatopontin.
Phe-Met-Arg-Phe-N[H.sub.2] (FMRF-amide), RAB37, and myomodulin transcripts, which were identified in the FG-versus-HG comparison, were significantly higher in abundance in the FG cohort than in the HG cohort (Fig.
RAB37 is a member of the Ras oncogene family, which is localized to secretory granules and is established as having a regulatory role in secretion (Fukuda 2008).