RAB32

RAB32

A gene on chromosome 6q24.3 that encodes a member of the Rab subfamily of Ras-related small GTPases, which plays a key role in vesicle targeting. RAB32 acts as an A-kinase anchoring protein by binding to the regulatory subunit of protein kinase A and anchoring it to the mitochondrion.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Different proteins have been identified by proteomic analysis, mostly classified into three groups: (1) structural proteins, such as the members of the PAT (perilipin-ADRP-TIP47) family and the cell death-inducing DFF45-like effector (CIDE) family; (2) membrane-trafficking proteins, including but not limited to Rab10, Rab18, Rab32, and Arf1 proteins and soluble NSF attachment protein receptors (SNAREs); and (3) enzymes implicated in lipid synthesis, such as DGAT2, and catabolism, such as ATGL and HSL [8, 25].
In this context, Rab GTPases are the most abundant class of proteins associated to LDs, even though, only for some of them, such as Rab1, Rab5, Rab10, Rab18, and Rab32, a functional interaction with LDs has been reported [68, 71].
Chen et al., "Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy," Nature Genetics, vol.