RAB31

RAB31

A gene on chromosome 18p11.3 that encodes a member of the Rab subfamily of Ras-related small GTPases, which plays a key role in vesicle targeting.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Many other genes might also be involved in the pathogenesis of UM such as the Ras and EF-hand domain containing (RASEF) gene, RAB31, hTERT, embryonal fyn-associated substrate, and deleted in split-hand/split-foot 1.
The extensive promoter hypermethylation was also observed in an independent cohort of 67 UM samples.[30] Interestingly, the study found that out of the 12 genes that were previously reported to be associated with metastatic risk of UM.[31] Only RAB31 , a member of the RAS oncogene family, showed differential methylation between normal uvea and UM.
Soelch et al., "Inverse association of rab31 and mucin-1 (CA15-3) antigen levels in estrogen receptor-positive (ER+) breast cancer tissues with clinicopathological parameters and patients' prognosis," American Journal of Cancer Research, vol.
In addition, other Rabs that are implicated in intracellular GLUT4 traffic include Rab4 [60], Rab5 [61], Rab11 [62], Rab28 [63], and Rab31 [64].
Chang et al., "Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes," Cell Metabolism, vol.
Autophagy-associated proteins Rab1a and Rab31 were identified as targets of both miRNAs.