In muscle cells, it has been shown that Rab8 and Rab13 are the major targets of AS160, whose downregulation profoundly inhibits insulin-stimulated GLUT4 translocation [56-59].
Klip, "Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells," Proceedings of the National Academy of Sciences of the United States of America, vol.
participates in ectoplasmic specialization dynamics in the rat testis.
It has been widely reported that Rab proteins of the endocytic pathway (e.g., Rab25, Rab13
, Rab23, and Rab5) and the constitutive secretory pathway (e.g., Rab8) play significant roles in malignancy [20, 27-30].
participates in ectoplasmic specialization dynamics in the rat testis," Biology of Reproduction 80(3): 590-601.
Klip, "A complex of Rab13
with MICAL-L2 and a-actinin-4 is essential for insulin-dependent GLUT4 exocytosis," Molecular Biology of the Cell, vol.