Q-banding stain

Q-band·ing stain

a fluorescent stain for chromosomes that produces specific banding patterns for each pair of homologous chromosomes; centromeric regions of human chromosomes 3, 4, and 13 are specifically stained, as are satellites of some acrocentric chromosomes and the end of the long axon of the Y chromosome; banding patterns are similar to those obtained with G-banding stain; similar fluorescent stain results are seen with the antibiotics adriamycin and daunomycin, as well as tertiary dyes (for example, butyl proflavine and DAPI), and the bisbenzimidazole dye Hoechst 33258.
Farlex Partner Medical Dictionary © Farlex 2012

Q-band·ing stain

(band'ing stān)
A fluorescent stain for chromosomes that produces specific banding patterns for each pair of homologous chromosomes; the acridine dye derivative quinacrine hydrochloride or other derivatives such as quinacrine mustard dihydrochloride produce a green-yellow fluorescence at pH 4.5 in chromosome segments rich in constitutive heterochromatin with deoxyadenylate-deoxythymidilate (A-T) bases of DNA; centromeric regions of human chromosomes 3, 4, and 13 are specifically stained, as are satellites of some acrocentric chromosomes and the end of the long arm of the Y chromosome.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012