Q-TWiST


Also found in: Acronyms.

Q-TWiST

Time without symptoms or toxicity; a quality of life measurement.
[acronym, quality time without symptoms or toxicity]
Farlex Partner Medical Dictionary © Farlex 2012
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In patients with BRCA wild-type carcinoma, longer Q-TWiST was also observed in the Rubraca treated arm, regardless of LOH status.
Q-TWiST results were derived by subtracting from the survival endpoint all time in which patients experienced treatment toxicity or disease symptoms, and then multiplying this area under the curve by a patient-derived utility value.
Q-TWiST therefore adds additional value not available in a traditional TWiST analysis because it reflects patients' perceptions of the impact of toxicity on the survival endpoint.