pyropoikilocytosis

py·ro·poi·ki·lo·cy·to·sis

(pī'rō-pōy-ki'lō-si-tō-sis),
A rare recessive disorder manifested by severe hemolysis, marked poikilocytosis, and a characteristic sensitivity of the red cells to heat-induced fragmentation in vitro; apparently due to a defect in spectrin self-association.

pyropoikilocytosis

[pī′rōpoi′kilō′sītō′sis]
a recessive inherited disorder characterized by severe hemolysis, irregular shapes of red blood cells, and sensitivity of blood cells to fragmentation in vitro after minor temperature variations.

pyropoikilocytosis

(pī″rō-poy″ki-lŏ-sī-tō′sĭs) [ pyro- + poikilocytosis]
An inherited form of hemolytic anemia in which cells have defective spectrin in their cytoskeleton, resulting in cellular breakdown during exposure to heat.
References in periodicals archive ?
Hereditary spherocytosis RBC spectrin RBC ankyrin Hereditary elliptocytosis RBC spectrin Hereditary pyropoikilocytosis RBC spectrin Hemolytic anemia - Glucose- G-6-PD 6-phosphate dehydrogenase deficiency Hereditary nonspherocytic PDH hemolytic anemia - Pyruvate kinase deficiency Porphyrias Various genes encoding enzymes of the heme biosynthesis pathway