pyridostigmine


Also found in: Encyclopedia, Wikipedia.

pyridostigmine

 [pir″ĭ-do-stig´mēn]
an anticholinesterase; used as the bromide salt in the treatment of myasthenia gravis and as an antidote to nondepolarizing neuromuscular blocking agents such as tubocurarine.

Mestinon

An oral agent used to manage myasthenia gravis.

Adverse effects
• Muscarinic—Nausea, vomiting, diarrhoea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis, diaphoresis; reversed with atropine.
• Nicotinic—Muscle cramps, fasciculation and weakness.

pyridostigmine

Mestinon® Pharmacology A cholinergic used to manage Pts with myasthenia gravis, including crises Adverse effects ↑ salivation, fasciculation, abdominal cramps, diarrhea. See Reversal agent.

pyridostigmine

A CHOLINERGIC drug used in the treatment of MYASTHENIA GRAVIS. The drug is on the WHO official list. A brand name is Mestinon.
References in periodicals archive ?
8 sgb v for medicines containing the active ingredient pyridostigmine (atc code: N07aa02) within the period from 1.6.2019 to 31.5.2021 with possibility of contract conclusion at any time (open-house model).
Pyridostigmine was discontinued, and the patient was discharged symptom-free and in good health.
Our patients have responded to erythromycin, octreotide, neostigmine, pyridostigmine, trimebutine maleate, domperidone, and laxative treatments.
The patient's blood glucose was regulated with intensive insulin treatment, the ptosis improved with pyridostigmine and diabetes education was completed.
Pyridostigmine, an acetylcholinesterase inhibitor that potentiates neurotransmissionin autonomic ganglia, amplifies sympathetic activation in response to orthostatic stress.
Pyridostigmine bromide 60 mg/d was initiated and the dosage was increased up to 360 mg/d.
He was started on prednisone 40 mg daily and pyridostigmine 120 mg four times daily, two and a half months prior to admission, and azathioprine 150 mg daily, 10 days prior to admission.
(a) (b) [] Diazepam [] [] [] Atropine [] [] [] Neostigmine [] [] [] Scopolamine [] [] [] Pyridostigmine [] [] True Wrong (a) (c) [] Diazepam [] [] [] [] [] Atropine [] [] [] [] [] Neostigmine [] [] [] [] [] Scopolamine [] [] [] [] [] Pyridostigmine [] [] [] [] Probably Probably True true wrong Wrong
In cases where snake envenomation and tick are less likely (or have been ruled out) and the index of suspicion for MG is high, the clinical response to a test dose of edrophonium or pyridostigmine may be a good diagnostic option.
The diagnosis of myasthenia gravis was performed; thus, patient started on pyridostigmine 180 mg/day and prednisone 25 mg/day, with no evident benefit.
Ptosis was reduced on the sixth day of pyridostigmine (3 mg/kg p.o.) and pyridoxine (150 mg/[m.sup.2] oral) treatment.
We started treatment with pyridostigmine and recommended surgical extirpation of mediastinal tumor, which was done two weeks later (Fig.