PAPA syndrome

(redirected from Pyogenic Sterile Arthritis)

PAPA syndrome

(pah'pah sin'drōm),
An autosomal dominant syndrome consisting of pyogenic sterile arthritis, pyoderma gangrenosum, and acne.
A rare autosomal dominant [MIM 64416] condition characterised by the acronym PAPA:
pyogenic arthritis
pyoderma gangrenosum and
cystic acne
Lab Hypogammaglobulinaemia, elevated tumour necrosis factor-alpha
Management Intra-articular corticosteroid therapy, methotrexate, colchicine
References in periodicals archive ?
Turner et al., "Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne)," Arthritis & Rheumatism, vol.