Purple Urine Bag Syndrome

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A rare ‘condition’ in which the urine in a bag from a catheterised patient turns an intense purple hours to days after catheterization. The rare phenomenon has been described in elderly women, and is linked to infection of the urine by Providentia stuartii which has indoxyl sulfatase-like activity, converting urinary indoxyl sulfate into indigo
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Interestingly, there is no other cause for purple urine other than purple urine bag syndrome.
Umeki, "Purple urine bag syndrome (PUBS) associated with strong alkaline urine," Kansenshogaku Zasshi, vol.
Purple urine bag syndrome. Emerg Med J 2015;32: 347.
Enzymatic degradation of urinary indoxyl sulfate by Providencia stuartii and Klebsiella pneumoniae causes the purple urine bag syndrome. J Clin Microbiol 1988; 26:2152-6.
Purple urine bag syndrome. Singapore Med J 2009; 50:e193-4.
The first article on purple urine bag syndrome (PUBS) was published in 1978.
Report of three cases of purple urine bag syndrome which occurred with a combination of both E.
Purple urine bag syndrome (PUBS) was first described by Barlow and Dickson in 1978.
Two cases and a short discussion of purple urine bag syndrome. CME Geriatr Med.
The pathogenesis of purple urine bag syndrome is due to the metabolism of tryptophan by bacteria to indole and later converted to indicant in the liver.[sup.3] This is excreted and broken down in the urine by bacteria possessing one or both enzymes, sulphatise and phosphatase that metabolize this pigment to indirubin and indigo in an alkaline environment (urine).
KEY WORDS: Purple urine bag syndrome, urinary catheter, urinary tract infection