Purkinje cell


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.
Related to Purkinje cell: nerve cell, Purkinje cell layer

Purkinje cell

(pûr-kĭn′jē)
n.
A large, drop-shaped, densely branching neuron that is the characteristic cell of the cerebellar cortex.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Purkinje cell

A large cerebellar cortex neuron with an ornate, antler-shaped dendritic arbor. Purkinje cells receive inputs (climbing fibers) from the inferior olive, and they send their axons (inhibitory) to the cerebellar and vestibular nuclei.
Synonym: Purkinje neuron
Medical Dictionary, © 2009 Farlex and Partners

Purkinje cell

a specialized NEURONE of the CEREBELLUM consisting of an axon, a large cell body and a single dendrite which is much branched, like a tree.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
(B) Multiple neighboring Purkinje cells are segmentally necrotic, indicated by the presence of shrunken, angular, and hypereosinophilic nuclei (*) (Scale bar = 50 [micro]m).
In the new paper, the researchers took their observations to humans, studying Purkinje cells derived from three patients with TSC (two also had ASD symptoms, and all three also had epilepsy).
The cortex further has three layers-molecular, Purkinje cell layer and granule cell layer.
Hayashi et al., "[alpha]-Synuclein accumulates in Purkinje cells in Lewy body disease but not in multiple system atrophy," Journal of Neuropathology and Experimental Neurology, vol.
Greenlee, "Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics," Journal of Neuroinflammation, vol.
The internal granular cell neuron layer was enlarged, separated by increased neuropil with scanty Purkinje cells. The cerebellar molecular layer was thickened with an abundance of radial processes.
All three trimester binge alcohol exposure causes fetal cerebellar purkinje cell loss in the presence of maternal hypercapnea, acidemia, and normoxemia: Ovine model.
* P < 0.05 Table 2: Comparison of stereological parameters in the cerebellum of noise-exposed (NE) and respective controls at postnatal day 22 Control (n = 8) NE (n = 8) Volume ([mm.sup.3]) Molecular layer 35.5 [+ or -] 2.1 34.6 [+ or -] 1.0 Granular layer 27.0 [+ or -] 1.3 25.4 [+ or -] 1.2 White matter 22.1 [+ or -] 1.2 21.6 [+ or -] 0.7 Total number (x 106) Granule cells 41.4 [+ or -] 4.5 35.5 [+ or -] 2.3 Somal volume ([micro] [m.sup.3]) Purkinje cell 3699 [+ or -] 236 3128 [+ or -] 398 P value Volume ([mm.sup.3]) Molecular layer 0.29 Granular layer 0.02 White matter 0.34 Total number (x 106) Granule cells 0.005 Somal volume ([micro] [m.sup.3]) Purkinje cell 0.004 All value are expressed as mean [+ or -] SD
Sugimori, "Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices," The Journal of Physiology, vol.
Verkerk's sinoatrial model [11], Butters's atrial model [12], O'Hara's ventricular model [13], and Li's Purkinje cell model [14], and so forth, all belong to HH model type.