(redirected from Purine nucleotides)
Also found in: Dictionary, Thesaurus, Encyclopedia.


a heterocyclic compound that is the nucleus of the purine bases such as adenine and guanine (which occur in DNA and RNA), and xanthine and hypoxanthine.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pur·ine (Pur),

(pyūr'ēn, -rin),
The parent substance of adenine, guanine, and other naturally occurring purine "bases."
Farlex Partner Medical Dictionary © Farlex 2012


1. A double-ringed, crystalline organic base, C5H4N4, that is the parent compound of a large group of biologically important compounds.
2. Any of a group of substituted derivatives of purine, including the nitrogen bases adenine and guanine, which are components of nucleic acids. Uric acid, caffeine, theobromine, and theophylline are also purines.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


The parent substance of adenine, guanine, and other naturally occurring so-called purine bases; not known to exist as such in mammals.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


one of two types of base found in NUCLEIC ACIDS, having a double ring structure; see ADENINE and GUANINE. Purines always pair with PYRIMIDINES in the two strands of DNA, ensuring a parallel-sided molecule.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005


A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
Mentioned in: Gout, Uric Acid Tests
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Caption: Figure 3: SDS-PAGE of expression products of biosynthetic genes of purine nucleotides in H.
Eight primers of the gene-encoding enzymes involved in purine nucleotide biosynthesis (Table S3, Supporting Information), as well as thirteen primers of the gene-encoding enzymes involved in pyrimidine nucleoside biosynthesis (Table S4, Supporting Information), were used to amplify the target products.
For purine nucleotide biosynthesis, 7 upregulated and 1 downregulated genes were quantified by real-time PCR (Figure S5, Supporting Information).
Serum levels of Co[Q.sub.10] in MS patients significantly interfere with the metabolism of purine nucleotides in CSF (Table 4(b)).
The results presented suggest that, in patients with multiple sclerosis (MS) alteration in the metabolism of purine nucleotides (Table 2), reduced antioxidant and neuroprotection (Table 3) occur, and is associated with increased intrathecal synthesis of IgG.
Acording to previous reports about AZA [4], seemingly obvious explanation could be that AZA selectively inhibit synthesis of purine nucleotides, which are required for DNA synthesis.
Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleotide phosphorylase deficiency.