Pulmonary Valve Insufficiency

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Pulmonary Valve Insufficiency



Pulmonary valve insufficiency is a disorder involving a defect of the valve located in the pulmonary artery.


This disorder is also known as pulmonary valve regurgitation or pulmonary incompetence. The pulmonary valve is the structure in the pulmonary artery consisting of three flaps, which open and close during each heartbeat. The flaps keep blood from flowing back into the heart from the pulmonary artery-the artery that supplies blood to the lungs. With pulmonary valve insufficiency, the flaps may allow the blood to flow backward, resulting in a distinct murmur. The disorder may be congenital, but also often occurs in patients with severe pulmonary hypertension.

Causes and symptoms

There are generally few to no symptoms with pulmonary valve insufficiency. It may be initially noticed as a murmur in a routine exam of the heart and chest with a stethoscope. The most common causes of the disorder are severe pulmonary hypertension, or the presence of high pressure in the arteries and veins of the lungs. Pulmonary hypertension is usually caused by chronic lung disease, lung blood clots, and sometimes other diseases, such as endocarditis, an inflammation of the lining of the heart and valves. Previous surgery for congenital heart disease may also cause pulmonary valve insufficiency.


The pitch and location of the murmur will help a physician determine if the cause is pulmonary valve insufficiency. An electrocardiogram (EKG) can detect flow changes. Echocardiography with color Doppler can usually detect regurgitation of blood in the area. This exam is done with ultrasound imaging. A chest x ray may show prominence of the pulmonary artery. In some cases, angiocardiography, or x ray of the arteries and vessels with injection of a dye, may be ordered.


On its own, pulmonary valve insufficiency is seldom severe enough to require treatment. Antibiotics are usually recommended before dental work to reduce the possibility of bacterial endocarditis. Management of the primary condition, such as medications to manage pulmonary hypertension, may help control pulmonary valve insufficiency.

Alternative treatment

Since there are few or no symptoms and the disorder is a structural defect, alternative treatment may have only limited usefulness. Proper diet, exercise, and stress reduction may help control hypertension. Coenzyme Q10 and hawthorn (Crataegus laevigata) are two important nutrients to nourish the heart. Antioxidant supplements (including vitamins A, C, and E, selenium, and zinc) can help keep the tissues of the whole body, including the heart, in optimal condition.

Key terms

Congenital — Used to describe a condition or defect present at birth.
Endocarditis — Inflammation of the lining of the heart and valves.
Prophylaxis — Preventive. Antibiotic prophylaxis is the use of antibiotics to prevent a possible infection.
Pulmonary — Refers to the lungs and the breathing system and function.
Pulmonary hypertension — High blood pressure in the veins and arteries of the lungs.


Patients with this disorder may never experience limitations from pulmonary valve insufficiency. The disorder may only show up if complicated by pulmonary hypertension. There is an increased incidence of bacterial endocarditis in patients with pulmonary valve insufficiency. Endocarditis can progress rapidly and be fatal.


Pulmonary valve insufficiency resulting from chronic lung diseases can be prevented by behaviors and interventions to prevent those primary diseases. Bacterial endocarditis resulting from pulmonary valve insufficiency can usually be prevented with the use of antibiotic prophylaxis in preparation for dental procedures or other procedures which may introduce bacteria into the bloodstream.



American Heart Association. 7320 Greenville Ave. Dallas, TX 75231. (214) 373-6300 or (800) 242-8721. inquire@heart.org http://www.americanheart.org.
National Heart, Lung and Blood Institute. P.O. Box 30105, Bethesda, MD 20824-0105. (301) 251-1222. http://www.nhlbi.nih.gov.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.


inability to perform properly an allotted function; called also incompetence.
adrenal insufficiency abnormally diminished activity of the adrenal gland; called also hypoadrenalism.
adrenocortical insufficiency abnormally diminished secretion of corticosteroids by the adrenal cortex; see also addison's disease. Called also hypoadrenocorticism and hypocorticism.
aortic insufficiency inadequate closure of the aortic valve, permitting aortic regurgitation.
coronary insufficiency decreased supply of blood to the myocardium resulting from constriction or obstruction of the coronary arteries, but not accompanied by necrosis of the myocardial cells. Called also myocardial ischemia.
ileocecal insufficiency inability of the ileocecal valve to prevent backflow of contents from the cecum into the ileum.
mitral insufficiency inadequate closure of the mitral valve, permitting mitral regurgitation.
placental insufficiency dysfunction of the placenta, with reduction in the area of exchange of nutrients; it often leads to fetal growth retardation.
pulmonary valve insufficiency inadequate closure of the pulmonary valve, permitting pulmonic regurgitation.
respiratory insufficiency see respiratory insufficiency.
thyroid insufficiency hypothyroidism.
tricuspid insufficiency incomplete closure of the tricuspid valve, resulting in tricuspid regurgitation.
valvular insufficiency failure of a cardiac valve to close perfectly, causing valvular regurgitation; see also aortic, mitral, pulmonary, and tricuspid insufficiency.
velopharyngeal insufficiency inadequate velopharyngeal closure, due to a condition such as cleft palate or muscular dysfunction, resulting in defective speech.
venous insufficiency inadequacy of the venous valves and impairment of venous return from the lower limbs (venous stasis), often with edema and sometimes with stasis ulcers at the ankle.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
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