Studies testing if 9-THC is the only responsible for cannabis psychoactivity conclude that administration of pure 9-THC and whole plant material produce similar effects, which do not significantly differ (Ilan et al., 2005; Wachtel et al., 2002).
To our knowledge it is the first systematic literature review focusing on psychoactivity, considering pharmacodynamical properties and potencies of several cannabinoids.
Working on a standard cannabis unit which quantifies cannabis main cannabinoid with implication on psychoactivity is needed.
Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain.
2008 Incensole acetate, anincense component, elicits psychoactivity by activating TRPV3 channels in the brain.
of ibotenic acid has been pegged at 1 mg/kg (Ott 1993), making Waser's dose a very light one.
However, Rhodes and Stimson (32) underline that psychoactivity
does not determine whether behaviour is disinhibited or controlled: it simply provides an empty vessel of altered consciousness for culture, circumstance and personality to load with meanings and explanations.
(21.) In DSM-IV and DSM-IV-TR there is no explicit requirement that dependence-producing substances be psychoactive; however, as already mentioned, the steroid literature tends to use the earlier version of the DSM and maintains the view that psychoactivity
is a crucial issue.
Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity
, is secreted into the storage cavity of the glandular trichomes.
The activity following its ingestion was described as "a peaceful elevation of mood, the generation of an euphoric state, and the enhancement of visual perception especially in the color sense." Preliminary human trials have shown that lophophine has some psychoactivity
in the 150 to 250 milligram range, but the full active dosage has not yet been determined (Shulgin 1991, 1979, 1976).
Cannabis was initially introduced to California in the form of hemp by the Spanish, who cultivated it as a fiber crop at the missions.(3) Small-scale experiments with hemp cultivation continued sporadically into the 20th century in the Sacramento Valley and later in Imperial County.(4) There is no reason to suspect that either the Spanish or the native peoples knew of its psychoactive or medical properties.(5) American-grown cannabis sativa was thought to have negligible psychoactivity
, being thereby distinguished from medical-grade cannabis indica, which was imported from India via England.
An emerging consensus is that "psychoactivity
does not determine whether behavior is disinhibited or controlled: it simply provides an empty vessel of altered consciousness for culture, circumstance and personality to load with meanings and explanations" (Room, 1983, pp.