Bakuchiol [(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-l-yl]phenol, a prenylated phenolic monoterpene found in the seeds and leaves of various plants, particularly Psoralea corylifolia
, has been used to treat a broad array of disorders, including skin conditions, in the traditional medical practices of China, Japan, and Korea, as well as Ayurvedic medicine in India.
Wright, The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia
and Sanguinaria canadensis, J.
Insecticidal and genotoxic activity of Psoralea corylifolia
 reported bactericidal activity of bakuchiol (obtained from Psoralea corylifolia
) on different Streptococcus, Enterococcus, and Lactobacillus species and Actinomyces viscosus and P.
Wenget al., "Development of an HPLC method for absolute quantification and QAMS of flavonoids components in Psoralea corylifolia
L," Journal of Analytical Methods in Chemistry, vol.
Psoralidin, for example, a natural phenolic compound found in the seeds of Psoralea corylifolia
, has been seen to inhibit NOTCH1 in breast cancer stem cells and in breast cancer cells, leading to a growth arrest and inhibition of epithelial to mesenchymal transition (EMT) .
Furocoumarins are found in natural plant extracts belonging to angiosperm families, formerly used in popular medicine: for example, angelicin is present in Angelica archangelica (Apiaceae), allopsoralen in Mammea americana (Guttiferae), and psoralens in Psoralea corylifolia
(Leguminosae) and Amni majus (Apiaceae) [4-6].
Wu, "Characterization of compounds in psoralea corylifolia
using high-performance liquid chromatography diode array detection, time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry," Journal of Chromatographic Science, vol.
Traditional Chinese Medicine Psoralea corylifolia
Psoraiidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia
Fecundity and fertility control of red cotton bug (Dysdercus cingulatus) by the extract of Psoralea corylifolia