pseudouridine

(redirected from Pseudouridylation)

pseu·do·u·ri·dine (Ψ, Q),

(sū'dō-yū'ri-dēn),
5-β-d-Ribosyluracil; a naturally occurring isomer of uridine found in transfer ribonucleic acids; unique in that the ribosyl is attached to carbon (C-5) rather than to nitrogen; excreted in urine.

pseu·do·u·ri·dine

(Ψ, Q) (sū'dō-yŭr'i-dēn)
A naturally occurring isomer of uridine found in transfer ribonucleic acids; unique in that the ribosyl is attached to carbon (C-5) rather than to nitrogen; excreted in urine.
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References in periodicals archive ?
Citation: Nicola Guzzi et al., "Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells," Cell, 2018; DOI: 10.1016/j.cell.2018.03.008
Based on different sequence motifs and secondary structures, snoRNAs are divided into two types: CD box snoRNAs, guiding ribose methylation, and H/ACA box snoRNAs which guide pseudouridylation [10, 11].
Dyskerin expression influences the level of ribosomal RNA pseudouridylation and telomerase RNA component in human breast cancer.
Kiss, "Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs," The EMBO Journal, vol.
There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation. snoRNAs are components of the small nucleolar ribonucleoproteins (snoRNPs), which are complexes responsible for the two aforementioned sequencespecific modifications: 2'-O-methylation and pseudouridylation.