Pseudomonas aeruginosa


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

Pseu·do·mo·nas ae·ru·gi·no·'sa

a bacterial species found in soil, water, and commonly in clinical specimens (wound infections, infected burn lesions, urinary tract infections); the causative agent of blue pus; occasionally pathogenic for plants; usually causes infections in humans in whom there is a defect in host defense mechanisms. It is the type species of the genus Pseudomonas.
Synonym(s): blue pus bacillus

pseudomonas aeruginosa

A normal soil inhabitant and human saprobe/commensal which may contaminate various solutions and fluids in a hospital, causing opportunistic infection in immunocompromised patients.
 
Clinical findings
Infective endocarditis in IV drug users, respiratory tract infections, urinary tract infections, bacteraemia, meningitis, “malignant” external otitis.

Management
Aminoglycosides—e.g., gentamicin, amikacin, netilmicin, tobramycin, etc. 

Pathogenesis
Pseudonomas aeruginosa is both invasive and toxicogenic, and infects patients in a 3-step process:
1. Bacterial attachment and colonization—mediated by pili and antiphagocytic effects of the organism’s polysaccharide capsule;
2. Local invasion—mediated by elastase and bacterial alkaline protease; and
3. Dissemination—high-dose tobramycin delivered by aerosol is reportedly effective in patients with cystic fibrosis.

Pseudomonas aeruginosa

A normal soil inhabitant and human saprophyte that may contaminate various solutions in a hospital, causing opportunistic infection in weakened Pts Clinical Infective endocarditis in IVDAs, RTIs, UTIs, bacteremia, meningitis, 'malignant' external otitis Treatment Aminoglycosides–eg, gentamicin, amikacin, tobramycin, etc

Pseu·do·mo·nas ae·ru·gi·no·sa

(sū-dō-mōnăz ē-rū-ji-nōsă)
Bacterial species found in soil, water, and commonly in clinical specimens (wound infections, infected burn lesions, urinary tract infections); produces blue pus.
Enlarge picture
Psuedomonas Aeruginosa: infection of the distal foot

Pseudomonas aeruginosa

A species that produces a distinctive blue-green pigment, grows readily in water, and may cause life-threatening infections in humans, including nosocomial pneumonia, urinary tract infections, and sepsis. It may also cause folliculitis, malignant otitis externa, and skin infections in patients who have suffered burns. See: illustration
See also: Pseudomonas
References in periodicals archive ?
Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aeruginosa biofilm matrix.
Suppression of fungal growth exhibited by Pseudomonas aeruginosa. Journal of Clinical Microbiology, 32: 525-527.
Sensitivity pattern of this study suggests that most active group of antibiotics against Pseudomonas infection is carbapenems and aminoglycosides, this was consistent with the findings of a study done at a Jamnagar, Gujrat, India by Kamria Pooja A, Aring J.B., Sinha Mala, out of 203 clinical isolates of Pseudomonas aeruginosa 85% (172) were sensitive to carbapenem group [13].
Antibacterial resistant Pseudomonas aeruginosa: Clinical impact and complex regulation of chromosomally encoded resistance mechanism.
Emergence of carbapenemase-producing Pseudomonas aeruginosa and Acinetobacter baumannii in livestock animals in Lebanon.
Evolution of antimicrobial resistance among Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae in Brooklyn, NY.
Yang et al., "Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective," Nature Reviews Microbiology, vol.
Detection of rhlAB, rhlR and rhlR genes in Pseudomonas aeruginosa natives overproducers of ramnolipids
The resistance produced by these pathogens has been mostly increased in Pseudomonas aeruginosa and Acinetobacter spp.
Objective: This study aims to determine the prevalence and susceptibility pattern of Pseudomonas aeruginosa and multidrug-resistant (MDR) isolates in patients suffering from respiratory tract infection.