PSEN2

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PSEN2

A gene on chromosome 1q31-q42 that encodes a probable catalytic subunit of the gamma-secretase complex, which catalyses the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP. It may play a role in intracellular signalling and gene expression, or in linking chromatin to the nuclear membrane; it may also play a role in sorting proteins in the cytoplasm.

Molecular pathology
Defects in PSEN2 are a cause of Alzheimer disease type 4 and cardiomyopathy dilated type 1V.
References in periodicals archive ?
He adds that gamers should see PS2 games that will start to push the limits of smoother, more sophisticated graphics--games that will feature characters and environments not only more realistic, but even mind-bendingly surrealistic.
Enter The Matrix ranked #1 among all PS2 titles for the month, #2 among all Xbox titles, and #6 among all GameCube titles, while Dragon Ball Z: Legacy of Goku II came in at #5 among all GBA titles, and Dragon Ball Z: Ultimate Battle 22 took the top spot among all PSX titles.
Pringles Original and Sour Cream and Onion (190g) tubes for PS2.
The CenDyne Wireless Xbox Network Adapter and CenDyne Wireless PS2 Network Adapter for PlayStation 2 enable gamers with an existing 802.