proximal tubule

(redirected from Proximal tubular)

proximal tubule

The first part of the tubular system of a nephron after the Bowman's capsule. It has convoluted and straight segments and is followed by the distal tubule.

proximal tubule

the convoluted tube between the loop of Henle and Bowman's capsule in the vertebrate kidney.
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References in periodicals archive ?
Plasma cell dyscrasia with kappa light-chain crystals in proximal tubular cells: a histological, immunofluorescent, and ultrastructural study.
Proximal Tubulopathies Associated With Monoclonal Light Chains: The Spectrum of Clinicopathologic Manifestations and Molecular Pathogenesis
Dent's disease is rare recessive X-linked renal tubular disorder manifesting by proximal tubular dysfunction of different grades, nephrolithiasis, nephrocalcinosis, rickets and slowly progressive renal failure.
Dent's disease type 1 in a boy with severe hyperopia and mental dysfunction: a case report
In the early stages of CsA administration kidney damage can occur, which causes alterations in intrarenal hemodynamics related to afferent arteriolar vasoconstriction, causing a decrease in glomerular filtration rate, renal plasma flow, loss of proximal tubular cells brush border, proximal tubule dilatation, swelling, necrosis, and infiltration of white blood cells in the kidney cortex.
Morphological evaluation of kidney following Cyclorsporine administration
Citation: "Rapid and Efficient Differentiation of Human Pluripotent Stem Cells into Intermediate Mesoderm that Forms Tubules Expressing Kidney Proximal Tubular Markers"; Albert Q.
Researchers generate kidney tubular cells from stem cells
Results of this study indicated that HOCM have a greater potential for cytotoxic effects on proximal tubular cells in vitro than do LOCM or IOCM.
Prevention of contrast-induced nephropathy through a knowledge of its pathogenesis and risk factors
have shown that, in cultures of proximal tubular cells, ANP inhibits the inducible nitric oxide synthase (iNOS) activity, via NPRC and cGMP [92].
Signaling pathways involved in renal oxidative injury: Role of the Vasoactive Peptides and the renal dopaminergic System
KIM-1 mRNA and protein are expressed at low levels in normal kidney but are specifically up regulated in de-differentiated proximal tubular cells after ischemic or nephrotoxic acute kidney injury (AKI).
Kidney injury molecule-1 expression is closely associated with renal allograft damage
Results showed that the renal proximal tubular-like cells generated by IBN were similar to the renal proximal tubular cells isolated from fresh human kidney samples.
Unlimited source of human kidney cells created
Of the different types of RTA associated with hypokalemia, distal RTA may be due to a defect in proximal tubular reabsorption found in the bicarbonate ion (HC[O.sub.3]) in type 2 RTA or a defect involving impaired distal tubular [H.sup.+] secretion in [H.sup.+]-ATPase/[H.sup.+][K.sup.+] ATPase (type 1 RTA).
Primary Sjogren's syndrome presenting with renal tubular acidosis and central pontine myelinolysis: a case report: renal tubuler asidoz ve santral pontin miyelinolizis ile seyreden primer Sjogren sendromu: olgu sunumu
Certain proximal tubular cells demonstrated varying degree of necrosis.
A study of oxidative stress in gentamicin induced nephrotoxcity and effect of antioxidant vitamin C in Wistar rats
Mellittin act on the apical membrane cell transporters of proximal tubular cell of the kidney thus reduce the cell viability and inhibit the activity of renal transporter.
Delayed onset renal failure following multiple bee stings
High glucose (HG) stimulated cultured human renal proximal tubular epithelial cells (HK-2) analyzed CTGF expression by Western blotting and investigated whether extracellular signal-regulated kinase (ERK) signaling pathway was involved.
Effect of loganin on experimental diabetic nephropathy

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