There was no significant improvement in the number of additional patients who received metformin, gliclazide, glibenclamide, protaphane
or actraphane in the intervention group and no significant increase in the mean dose of these medications.
Four patients administered three injections per day: Actraphane before breakfast, soluble insulin (Actrapid) before supper, and isophane insulin (Protaphane
) at 21h00, and only one was on a basal-bolus regimen (isophane insulin at 21h00 hours, with soluble insulin boluses before each meal).
Her GP reviewed these a few days later, and prescribed a daily dose of protaphane insulin to stabilise her BGL.
Her diabetes was being controlled by protaphane insulin, adjusted weekly.
Examples are Protaphane
(Novo Nordisk, Baulkham Hills, NSW) and Humulin NPH (Eli Lilly, West Ryde, NSW).