Misoprostol is the only prostaglandin [E.sub.1] analogue uterine stimulant that is currently commercially available in obstetrics and gynaecology; all other prostaglandin preparations, commercially known as Prostin
, Prandin, Prepidil, and by many other names, are prostaglandin [E.sub.2] analogues, and long preceded the use of misoprostol.
Group B comprised of 30 patients and received Prostin
E2 vaginal tablet (3mg) maximum of two doses.
Both Pfizer's Prostin
(PGE) and Cook Medical's Cervical Ripening Balloon (CRB) are licensed for IOL.
Patients with an unfavorable cervix (Bishop score < 6) received 2 mg Prostin
gel (1mg if there was prelabor rupture of membranes) in the posterior fornix of the vagina, repeating the dose after 6 hours if necessary, depending on the Bishop score (Prostin
E2, dinoprostonum 1 mg/3 g (RVG 13823) or 2 mg/3 g (RVG 13824), Pfizer B.V., Capelle aan de IJssel, The Netherlands).
Other items include a vial of the drug Prostin
which was used to keep babies alive until they were old enough for surgery and a T-shirt signed by members of the Young Person's Advisory Group.
(Hemabate) of 8 doses) Contra-indicated in hepatic, renal, and cardiac disease Dinoprostone 20 mg suppository Avoid in hypotension (Prostin
E2) can be given vaginally or rectally every 2 hours
The court heard Evan's mother was overdue when she was admitted to Sligo General Hospital and was given a dose of two milligrams of the drug Prostin
E2 to induce birth.
In the [PGE.sub.1] group, infusion of [PGE.sub.1] (Prostin
VR; Pharmacia & Upjohn, Puurs, Belgium) was started in the operating room just before induction of anaesthesia at a dose of 20 ng.[kg.sup.-1].[min.sup.-1] until the end of the operation and just before transfer to ICU.
Surprises of off-label drug use--where had all the Prostin
When first line therapy fails, the patient may use intracavernous injections of alprostadil (Caverject [R] or Prostin