Prostate specific antigen

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Related to Prostate specific antigen: Prostate Enlargement


A gene on chromosome 19q13.41 that encodes a serine protease with diverse physiological functions, which may also have a role in carcinogenesis. KLK3 hydrolyses semenogelin-1, leading to the liquefaction of the seminal coagulum.

PSA (Prostate specific antigen)

A tumor marker associated with prostate cancer.
Mentioned in: Tumor Markers

Patient discussion about Prostate specific antigen

Q. Would kidney stones affect a PSA reading? Would drinking lots of grapefruit juice affect a PSA reading? My husband's PSA reading jumped from a 4.2 to a 17 in @ 2 years' time. How can that be? This man takes all sorts of supplements and really watches his diet. He also takes good care of his body, and does NOT look or act 68.

A. You should get your parathyroid gland checked out. Your calcium level might be causing the kidney stones.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.

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References in periodicals archive ?
Prostate specific antigen best practice statement: 2009 Update.
Diagnosis of prostatic carcinoma; the yield of serum prostate specific antigen, digital rectal examination and transrectal ultrasonography.
Pro PSA: a more cancer specific form of prostate specific antigen for the early detection of prostate cancer.
The importance of human glandular kallikrein and its correlation with different prostate specific antigen serum forms in the detection of prostate carcinoma.
The screening is a simple blood test that checks the level of Prostate Specific Antigen (PSA) in the blood stream.
Prostatic volume and ratio of free-to-total prostate specific antigen in patients with prostatic cancer or benign prostatic hyperplasia.

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