propylene glycol

(redirected from Propylene glycols)
Also found in: Dictionary, Thesaurus, Encyclopedia.

propylene glycol

 [pro´pĭ-lēn gli´kol]
a clear viscous liquid used as a moistening agent and solvent in pharmaceutical preparations.

pro·py·lene gly·col

a solvent for several water-insoluble drugs intended for parenteral administration; an ingredient of hydrophilic ointment; a viscous organic solvent frequently used in pharmaceutical preparations to dissolve drug substances with limited aqueous solubility; used in part for preparing injectable solutions of diazepam, phenytoin, pentobarbital, and other drugs.

prop·y·lene gly·col

(prōpi-lēn glīkol)
Solvent for several water-insoluble drugs intended for parenteral administration; used in part to prepare injectable solutions of diazepam, phenytoin, and drugs.
References in periodicals archive ?
Disterhoft, "Caution against using propylene glycol as a solvent in epilepsy drug research," Neuroscience Research Communications, vol.
Crittenden, "Protection from Oxygen-Induced Seizures by Clonazepam and Propylene Glycol (41232)," Proceedings of the Society for Experimental Biology and Medicine, vol.
Neilen et al., "Propylene glycol pharmacokinetics and effects after intravenous infusion in humans," Therapeutic Drug Monitoring, vol.
[17] "NTP-CERHR Expert Panel report on the reproductive and developmental toxicity of propylene glycol," Reproductive Toxicology, vol.
Goodman, "Hyperosmolality in small infants due to propylene glycol," Pediatrics, vol.
MacDonald, "Propylene glycol: increased incidence of seizures in low birth weight infants," Pediatrics, vol.
Gupta, "Development and evaluation of a guideline for monitoring propylene glycol toxicity in pediatric intensive care unit patients receiving continuous infusion lorazepam," The Journal of Pediatric Pharmacology and Therapeutics, vol.
Finberg, "Propylene glycol: a potentially toxic vehicle in liquid dosage form," The Journal of Pediatrics, vol.
Genel, "Central nervous system toxicity associated with ingestion of propylene glycol," Journal of Pediatrics, vol.
Bailey, "Propylene glycol as a cause of lactic acidosis," Journal of Analytical Toxicology, vol.
Kelly, "Propylene glycol toxicity in a pediatric patient: the dangers of diluents," Journal of Pharmacy Practice, vol.