propofol


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propofol

 [pro´pah-fol]
a short-acting sedative and hypnotic used as a general anesthetic and adjunct to anesthesia; administered intravenously.

pro·po·fol

(prō'pō-fōl),
An oil-in-water emulsion of 1,6-diisopropylphenol, a hypnotic with rapid onset and short duration of action; used intravenously for induction and maintenance of general anesthesia.
Synonym(s): 2, 6-diisopropyl phenol

propofol

/pro·po·fol/ (pro´pah-fol) a short-acting sedative and hypnotic used as a general anesthetic and adjunct to anesthesia.

propofol

(prō′pō-fôl′, -fōl′)
n.
A rapidly acting sedative and hypnotic drug, C12H18O, administered intravenously to induce and maintain anesthesia or sedation.

propofol

[pro′pah-fol]
a short-acting sedative and hypnotic used as a general anesthetic and adjunct to anesthesia, administered intravenously.

propofol

Diprivan® Anesthesiology A versatile nonopioid inhalation sedative-hypnotic with rapid–< 45 secs onset, used to induce and maintain anesthesia, and possibly control refractory status epilepticus; it ↓ intracranial and intraocular pressure, cerebral blood flow, and O2 consumption Pros Ideal for conscious sedation; useful for critically ill Pts; can be combined with other agents–eg, volatile anesthetics, NO2, opiates or benzodiazepines; little post-op N&V Adverse effects Profound respiratory depression ± transient apnea; injection site pain, hypotension Indications Short procedures or outpatient surgery Contraindications Hemodynamically unstable Pts. See Meyer-Overton rule. Cf Inhalation anesthetic, Opioid anesthetic.

pro·po·fol

(prō'pō-fōl)
Hypnotic agent with rapid onset and short duration of action; used intravenously to induce and maintain general anesthesia.

propofol

A general anaesthetic drug given by injection. A brand name is Diprivan.

pro·po·fol

(prō'pō-fōl)
A hypnotic with rapid onset and short duration of action; used intravenously for induction and maintenance of general anesthesia.
Synonym(s): 2,6-diisopropyl phenol, .

propofol (prō´pōfol),

n brand name: Diprivan;
drug class: general anesthetic;
action: produces dose-dependent central nervous system depression; mechanism of action is unknown;
use: induction or maintenance of anesthesia as part of a balanced anesthetic technique.

propofol

a rapidly acting, short duration, intravenous hypnotic anesthetic induction agent, which has low excitatory effect. It is harmless when injected into tissues or intra-arterially. The active ingredient is 2,6-di-isopropylphenol.
References in periodicals archive ?
In summary, the results from the present study indicated that the protective effect of propofol against H/R injury in the HBVSMC was through the inhibition of apoptosis by inhibiting the expression levels of Bax, Caspase3, Kir6.
But Mr Murphy's death certificate was reissued last year to include propofol infusion syndrome - a recognised complication of long-term propofol use - as one of the causes of his death, alongside blunt force head injury.
Patients were divided into two groups: Group-1 consisted of one hundred patients sedated by nitrous oxide inhalation and Group-2 consisted of one hundred patients sedated by intravenous propofol and midazolam.
As a short-acting sedative-hypnotic agent, propofol is increasingly used for sedation during mechanical ventilation, especially for postoperative patients.
To meet the objectives of the present investigation, Internet search engines including PubMed, Medline, Ovid, Google[R], Google Scholar[R], and Cochrane were queried with the key words as medical subject headings to identify peer-reviewed scientific articles on fatal propofol abuse in the U.
Keywords: Thiopental, Ketamine, Propofol, Paediatric, Magnetic resonance imaging.
ICU patients sedated with propofol had a reduced risk of mortality and had both an increased likelihood of earlier ICU discharge and earlier discontinuation of mechanical ventilation.
This study was designed to determine induction and recovery times as well as the amount of drug used during propofol induction with TCI systems vs.
In 1989, the US Food and Drug Administration (FDA) approved propofol as an induction agent for general anesthesia.
2] Thus, we decided to compare the induction and recovery profiles of the propofol with thiopentone in day care patients.