Propionibacterium acnes

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Pro·pi·on·i·bac·te·ri·um ac·'nes

a species of bacteria commonly found in acne pustules, although it occurs in other types of lesions in humans and even as a saprophyte in the intestine, skin, hair follicles, and in sewage.

Propionibacterium acnes

A gram-positive bacillus that may be part of the normal skin flora, but can also be pathogenic in acne, wounds, and infected prosthetic devices. It was formerly called Corynebacterium acnes.


gram-positive pleomorphic rods which are common skin residents, found also in dairy products and the alimentary tract.

Propionibacterium acnes
activates macrophages, increases proliferation of lymphoblasts, and stimulates resistance to bacterial infection. Used as a bacterial immunostimulant.
References in periodicals archive ?
Fermentation of Propionibacterium acnes , a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus .
Pathological mechanisms of acne with special emphasis on Propionibacterium acnes and related therapy.
Many factors including androgenic stimulation, Propionibacterium acnes activity, sebum production, hypercornification, as well as inflammatory mediator responses are thought to play a role in acne pathogenesis.
Biofilm formation by Propionibacterium acnes on biomaterials in vitro and in vivo: impact on diagnosis and treatment.
Caption: Propionibacterium acnes is shown under magnification.
Objective: Follicular hyperkeratinization and Propionibacterium acnes colonization are mainly responsible for the pathogenesis of acne.
The pathogenesis of acne vulgaris is known to be multimodal, including ductal hypercor-nification, enhanced sebaceous gland activity, colonization by Propionibacterium acnes and inflammation.
The four major factors that are primarily involved in the pathogenesis of acne include increased sebum production, hypercornification of the pilosebaceous duct, abnormal colonization by propionibacterium acnes and inflammation.
The British Association of Dermatologists conference heard over-prescribing could cause the emergence of antibiotic-resistant Propionibacterium acnes.
29) The development of acne is characterized by the excessive production and oxidation of sebum--the skin's natural oil--that generates inflammation and is a breeding ground for bacteria called Propionibacterium acnes (P.
Acne begins with abnormal keratinization and a complex interplay between sebum production, hypersensitivity to androgen stimulation, changes in lipid compound, Propionibacterium acnes, and local inflammatory cytokines elaborated by the innate immune system.
The antibiotic angle makes total sense: You have bacteria, Propionibacterium acnes, playing what is thought to be a causative role in the pathogenesis of acne; you kill that bacteria; the acne improves.