propentofylline


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propentofylline

Neurology An agent that may help improve mental performance in dementia. See Dementia.

propentofylline

a xanthine derivative glial cell modulator used to improve cognitive function in senile dogs.
References in periodicals archive ?
No drugs have been approved to specifically treat feline CD, but veterinarians can prescribe some medications, such as selegiline and propentofylline, "off-label," as well as therapeutic diets intended to improve cognitive function.
Propentofylline in the treatment of vascular dementia and Alzheimer-type dementia: overview of phase I and phase II clinical trials.
Efficacy of propentofylline, a glial modulating agent, on existing mechanical allodynia following peripheral nerve injury.
The effects of local pentoxifylline and propentofylline treatment on formalin-induced pain and tumor necrosis factor-alpha messenger RNA levels in the inflamed tissue of the rat paw.
Propentofylline increases the oxygenation of tissue, especially the brain, heart and muscle.
Patients with Alzheimer's disease and vascular dementia responded well to propentofylline, a drug that may become available in the United States within the next few years.
Propentofylline is a phosphodiesterase inhibitor and an inhibitor of adenosine re-uptake.
In a multicenter prospective study that was conducted by the European-Canadian Propentofylline Study Group, 237 patients with Alzheimer's disease who took propentofylline showed improvements on tests of cognition and global functioning, relative to 241 patients with Alzheimer's who took a placebo, Dr.
Improvements also were demonstrated by 210 patients with vascular dementia who took propentofylline, compared with 224 patients with vascular dementia who took a placebo.
They were randomized to take 300 mg of either propentofylline or placebo three times a day.
Propentofylline in adult onset cognitive disorders: double-blind, placebo controlled, clinical, psychometric and brain mapping studies.