promoter

(redirected from Promoter region)
Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

pro·mo·ter

(prō-mō'tĕr),
1. In chemistry, a substance that increases the activity of a catalyst.
2. In molecular biology, a DNA sequence at which RNA polymerase binds and initiates transcription.
Farlex Partner Medical Dictionary © Farlex 2012

promoter

(prə-mō′tər)
n.
1. One that promotes, especially an active supporter or advocate.
2. A financial and publicity organizer, as of a boxing match or an artistic performance.
3. Genetics The region of an operon that acts as the initial binding site for RNA polymerase.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

pro·mo·ter

(prŏ-mō'tĕr)
1. chemistry A substance that increases the activity of a catalyst.
2. molecular biology A DNA sequence at which RNA polymerase binds and initiates transcription.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

promoter

In genetics, a nucleotide sequence at the start of a gene to which RNA polymerase must bind before the process of transcription can start. The promoter is located UPSTREAM of the gene it regulates.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

promoter

a cis- acting (see CIS -ACTIVE) NUCLEOTIDE sequence on a DNA molecule which promotes the initiation of TRANSCRIPTION by allowing the assembly of proteins, including RNA POLYMERASE (or its equivalent), in transcriptional complexes. see OPERON MODEL. The promoter generally lies UPSTREAM of the transcription start site.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Patient discussion about promoter

Q. I am interested in social service. So what can I do to promote a healthy pregnancy?

A. Hi friend, once you're pregnant, a regular checkup is the key. Your health professional might want to monitor your baby's growth and watch for problems that can only be detected by checking your blood pressure, urine, and blood regularly. Anything you do that harms your body harms your fetus. Take special care: To avoid: tobacco smoking, alcohol, drugs, chemicals, radiation (as from X-rays), and sources of infection. Keep your body temperature from getting too high [over 100.4° (38°)] by treating any fevers with acetaminophen (such as Tylenol) and avoiding exercise or activity that overheats you. Also avoid high-temperature hot tubs and saunas. Take extra-good care of yourself while you're pregnant. Everything healthy you do for your body benefits your growing fetus. Rest when you need it, eat well, and exercise regularly.

More discussions about promoter
This content is provided by iMedix and is subject to iMedix Terms. The Questions and Answers are not endorsed or recommended and are made available by patients, not doctors.
References in periodicals archive ?
XBP1 contains several distinct binding elements relating to the promoter regions of several downstream genes, including ERSE, ERSE II, UPRE, and UPRE-II.
The wild type CC allele of the BCL-2 promoter region produced a single 252-bp fragment, the AC allele produced 252bp and 154bp fragments, and the AA allele produced 154bp and 98bp fragments.
Single nucleotide polymorphisms' differences in TNF-[alpha] gene's promoter region were assessed using logistic regression models.
In the current study it was shown 80 (83%) inhA mutation was contributed to transition of C to T at position -15 and 17.3% was due to T to C transition at position-8 in the promoter region of inhA gene.
Polymorphisms in the promoter region of the genes affect the transcriptional activity and also the gene products.
Since primers designated in the promoter region or exon 4 resulted in unspecific PCR products of MSP amplification (data not shown), we analyzed the methylation status of LC3A in exon 3 using primer designed to amplify 10 CpG dinucleotides.
Hurley, "Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents," Nucleic Acids Research, vol.
The IL-6 promoter region gene sequence was searched in the NCBI database, and the JASPAR database was used to predict the binding sites of the KLF7 and IL-6 promoter regions.
The ChIP study revealed that activation of PAR4 suppressed the enrichments of DNMT1 and HDAC2 on the p16 promoter region. These effects were associated with MAPK signals that were induced by PAR4 activation.
The deletion mutation studies of HSP70 gene unveiled the significance of certain sequences in the upstream promoter region such as CTGGAATATTCCCG which also matched to 12 out of the 14 sequences that were found in Drosophila heat shock genes (Wu, Kingston, and Morimoto, 1986).
Among these, 21(70%) had mutation in catalase-peroxidase gene and 2(6.6%) had C15T mutation in inhibin alpha promoter region. Among the 21 catalase-peroxidase mutants, Ser315Thr mutation was detected in 15(71.4%) isolates.
In this study, we detected SNPs in the promoter region of HLA-DQA1 in a relative large Chinese Han population to evaluate whether polymorphisms were associated with the susceptibility to IMN.