promoter

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pro·mo·ter

(prō-mō'tĕr),
1. In chemistry, a substance that increases the activity of a catalyst.
2. In molecular biology, a DNA sequence at which RNA polymerase binds and initiates transcription.

promoter

/pro·mo·ter/ (pro-mo´ter)
1. a segment of DNA usually occurring upstream from a gene coding region and acting as a controlling element in the expression of that gene.
2. a substance in a catalyst that increases its rate of activity.
3. a type of epigenetic carcinogen that promotes neoplastic growth only after initiation by another substance.

promoter

(prə-mō′tər)
n.
1. One that promotes, especially an active supporter or advocate.
2. A financial and publicity organizer, as of a boxing match or an artistic performance.
3. Genetics The region of an operon that acts as the initial binding site for RNA polymerase.

promoter

[-mō′tər]
Etymology: L, promovere, to move forward
1 a DNA sequence that initiates transcription of the genetic code.
2 a cocarcinogen that encourages cells altered by initiators to reproduce more rapidly than normal, increasing the probability of malignant transformation. Examples include chlorophenothane (DDT), phenobarbital, saccharin, sunlight, and some chemicals in cigarette smoke. The effects of promoters are sometimes reversible.

pro·mo·ter

(prŏ-mō'tĕr)
1. chemistry A substance that increases the activity of a catalyst.
2. molecular biology A DNA sequence at which RNA polymerase binds and initiates transcription.

promoter

In genetics, a nucleotide sequence at the start of a gene to which RNA polymerase must bind before the process of transcription can start. The promoter is located UPSTREAM of the gene it regulates.

promoter

a cis- acting (see CIS -ACTIVE) NUCLEOTIDE sequence on a DNA molecule which promotes the initiation of TRANSCRIPTION by allowing the assembly of proteins, including RNA POLYMERASE (or its equivalent), in transcriptional complexes. see OPERON MODEL. The promoter generally lies UPSTREAM of the transcription start site.

promoter

a specific DNA sequence to which RNA polymerase binds and signals where RNA synthesis (transcription) should begin.

internal promoter
a class of enhancers which are gene-specific sequences that increase transcription.
promoter region
the non-coding nucleotide sequence at the transcription start region that is characterized by the presence of a number of conserved or consequence sequences.

Patient discussion about promoter

Q. I am interested in social service. So what can I do to promote a healthy pregnancy?

A. Hi friend, once you're pregnant, a regular checkup is the key. Your health professional might want to monitor your baby's growth and watch for problems that can only be detected by checking your blood pressure, urine, and blood regularly. Anything you do that harms your body harms your fetus. Take special care: To avoid: tobacco smoking, alcohol, drugs, chemicals, radiation (as from X-rays), and sources of infection. Keep your body temperature from getting too high [over 100.4° (38°)] by treating any fevers with acetaminophen (such as Tylenol) and avoiding exercise or activity that overheats you. Also avoid high-temperature hot tubs and saunas. Take extra-good care of yourself while you're pregnant. Everything healthy you do for your body benefits your growing fetus. Rest when you need it, eat well, and exercise regularly.

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References in periodicals archive ?
In order to have a complete picture about the sequences of the HSPA6 gene and its predicted promoter region, we fused the sequence isolated in this study with the first 136bp of HSPA6 mRNA to generate a total of 1553bp.
From this study, we selected SNPs in the promoter region of HLA-DQA1 through RegulomeDB and analyzed their association with IMNs in a cohort of Chinese Han individuals.
Regarding allelic frequencies, the G allele was a risk factor for NP development in the TNF-[alpha]-308 promoter region (OR: 6.
A sensitivity analysis in which preterm births (n = 14 for total group; n = 12 for 3-NTp group), mothers with gestational diabetes/ hypertension (n = 20 for total group; n = 19 for 3-NTp group), and mothers with preeclampsia (n = 2 for both groups) were excluded showed very little change in the estimated associations between the overall placental methylation of the LEP promoter region and second-trimester [PM.
It is worth noting that among them, the Sp1-binding site was found to be functionally preserved in the Nanog proximal promoter region from both mouse and bovine.
During 20:00-8:00, electricity demand per unit of the buildings in promoter region is reduced, and electricity can be bought directly from the network for application.
A schematic diagram showing the truncated ChMT promoter regions and the primers used for amplification is shown in Figure 2.
In the present study, we determined the involvement of NOX-derived ROS in the TPA-elicited induction of Slug expression, which was closely associated with histone H3 acetylation within its promoter region (Figure 3).
Tobacco smoke has previously been associated with DNA hypermethylation of CpG sites within promoter regions and exons of tumor suppressor genes, and with global hypomethylation of DNA in HNSCC.
The SNPs in the IL-11 promoter region are in complete and/or absolute linkage disequilibrium, so that only three haplotypes (ACC, GCG and GGG) of the possible eight are observed.
Note this incorporates the T7 promoter region at one end of the molecule.