Progesterone Plus

Progesterone Plus

Gynecology A progesterone-replacement product from soy and/or wild yam extract applied to skin with Derma-Trans roll-on system. See Progesterone.
References in periodicals archive ?
Women were randomized to oral conjugated equine estrogens (0.45 mg per day) and oral progesterone (200 mg for 12 days per month); the same dose of oral progesterone plus transdermal 17-beta-estradiol (50 meg per day); or placebo.
Ovariectomized rats were randomly assigned to progesterone (PRO), estradiol (EST), progesterone plus estradiol (PRO + EST), or control ovariectomized (OVX) groups.
Additionally, in our study, although OVX rats given progesterone or progesterone plus estradiol and then treated with cocaine showed greater stereotypy behavior when compared to controls, they exhibited a lack of the stereotypy behaviors characteristic of cocaine sensitization.
Wendy Chen, suggests that opting for progesterone-free hormone therapy for the treatment of menopause symptoms should not be considered the risk-free alternative to combination progesterone plus estrogen formulations.
Chen stated, noting that women in the study who used progesterone plus estrogen for 10-14.9 years had an 88% increased risk of developing breast cancer relative to those not on HT and the risk increased to more than twofold in women using it for up to 20 years.
Wendy Chen at the annual meeting of the American Association for Cancer Research, suggests that opting for progesterone-free hormone therapy for the treatment of menopause symptoms should not be considered the risk-free alternative to combination progesterone plus estrogen formulations.
Chen stated, noting that women in the study who used progesterone plus estrogen for 10-14.9 years had an 88% increased risk of developing breast cancer relative to those not on HT, and the risk increased to more than twofold in women using it for up to 20 years.
The hormonal options are oestrogens alone, progesterone alone, or combinations and, since there are no published trials, a group from California chose to compare two regimens of progesterone only, or progesterone plus oestrogen in the form of a standard preparation oral contraceptive (Munro et al., Obstet Gynecol 2006; 108: 924-929).
In contrast, progesterone plus estradiol provided a reduction in atheroma equivalent to estradiol alone.
The finding suggests that opting for progesterone-free hormone therapy for the treatment of menopause symptoms should not be considered the risk-free alternative to combination progesterone plus estrogen formulations.
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