The discovery of novel methods allowing the purification of cardiovascular progenitors
during embryonic stem cell differentiation is thus essential before these cells could be used in large scale to treat patients suffering from cardiovascular diseases or for drug discovery.
Led by Associate Professors Jane Visvader and Geoff Lindeman, the researchers have discovered that luminal progenitor
cells are the likely source of basal-like breast tumours.
They instead transplanted iPSC-derived renal progenitors
into the kidney subcapsule, which is at the kidney surface of a mouse model with acute kidney injury.
Nevertheless, scientists have been trying to find ways to amplify the heart's limited regenerative potential and have looked for clues in the embryonic phase of life, when the heart forms itself from stem-like cardiac progenitor
October 30, 2014 -- UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor
stem cells are activated to fight infection.
Neurovascular Recovery via Cotransplanted Neural and Vascular Progenitors
Leads to Improved Functional Restoration after Ischemic Stroke in Rats"; Stem Cell Reports, 2014; DOI: 10.
cells then must undergo differentiation to oligodendrocyte progenitors
that are capable of ultimately producing the oligodendrocytes.
Brain neurons are generated from stem cells called basal progenitors
that are able to proliferate in humans, but not in mice.