procarbazine

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procarbazine

 [pro-kahr´bah-zēn]
an antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone in the regimen called MOPP for treatment of advanced Hodgkin's disease; it also has activity against non-Hodgkin's lymphomas and brain tumors.

procarbazine

/pro·car·ba·zine/ (pro-kahr´bah-zēn) an alkylating agent used as the hydrochloride salt as an antineoplastic, primarily in the treatment of Hodgkin's disease.

procarbazine

(prō-kär′bə-zēn)
n.
A potent antineoplastic drug, C12H19N3O, used in its hydrochloride form in combination with other drugs to treat advanced Hodgkin lymphoma.

MOPP

A 4-drug chemotherapy regimen for stage-III Hodgkin lymphoma.
 
Adverse effects
Sterility, nausea, vomiting, immunosuppression, increased infections, myelosuppression, myelodysplasia, ANLL.

procarbazine

Matulane® Oncology An alkylating therapeutic used as part of a multi-drug treatment for Hodgkin's disease Adverse effects BM suppression, N&V, neuropathy, confusion, swelling. See Hodgkins disease.

procarbazine

An anticancer drug used especially in the treatment of LYMPHOMAS. The drug is on the WHO official list. A brand name is Natulan.

procarbazine

an antineoplastic agent that acts by inhibiting the synthesis of DNA, RNA and protein.