primary ciliary dyskinesia


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dyskinesia

 [dis-ki-ne´zhah]
impairment of the power of voluntary movement.
primary ciliary dyskinesia any of a group of hereditary syndromes characterized by delayed or absent mucociliary clearance from the airways; often there is also lack of motion of sperm. One variety is Kartagener's syndrome.
tardive dyskinesia an iatrogenic disorder produced by long-term administration of antipsychotic agents; it is characterized by oral-lingual-buccal dyskinesias that usually resemble continual chewing motions with intermittent darting movements of the tongue; there may also be choreoathetoid movements of the extremities. The disorder is more common in women than in men and in the elderly than in the young, and incidence is related to drug dosage and duration of treatment. In some patients symptoms disappear within several months after antipsychotic drugs are withdrawn; in others symptoms may persist indefinitely.

primary ciliary dyskinesia

an apparently autosomal recessive disorder in which mucus clearance is sluggish and bronchiectasis is prevalent and intractable. Evidence suggests the defect lies in dynein, a protein in the cilia.
Synonym(s): dyskinesia syndrome

pri·ma·ry cil·i·ar·y dys·ki·ne·si·a

(prīmar-ē silē-ar-ē diski-nēzē-ă)
Disorder inwhich mucus clearance is sluggish and bronchiectasis is prevalent and intractable.
References in periodicals archive ?
Discordant organ laterality in monozygotic twins with primary ciliary dyskinesia. Am J Med Genet 1999;82(2):155-60.
Successful twin birth following blastocyst culture of embryos derived from the immotile ejaculated spermatozoa from a patient with primary ciliary dyskinesia: a case report.
Fertility in men with primary ciliary dyskinesia presenting with respiratory infection.
Nitric oxide in primary ciliary dyskinesia. Eur Respir J.
Congenital disorders are labeled as Primary ciliary dyskinesia [PCD].
Primary ciliary dyskinesia is an autosomal recessive disorder with incomplete penetrance [1].
Primary ciliary dyskinesia: a genome-wide linkage analysis reveals extensive locus heterogeneity.
Andrew, a carer for two of his children, Darryl, 13, and Tyler, five, who have primary ciliary dyskinesia (PCD), a rare inherited condition which can affect the lungs, sinuses and ears said: "The kids love football and I am proud of that because it keeps them active.
The young Boro fans have PCD (primary ciliary dyskinesia), an inherited condition affecting the tiny hair-like structures that move mucus out of the respiratory passages.
Darryl, 11, and Tyler have PCD (primary ciliary dyskinesia), an inherited condition affecting the tiny hair-like structures that move mucus out of the respiratory passages.
Kartagener's syndrome (KS) comes under larger group of ciliary motility disorders called primary ciliary dyskinesias (PCDs).