It included 367 CBC cases and a control group of 734 matched breast cancer survivors without a second primary cancer
were biopsied by TNE through a port on the endoscope in 4 patients; 2 of these cancers were in the tongue base, 1 in the hypopharynx, and 1 in the aryepiglottic fold.
Cancer statistics, trends, and multiple primary cancer
analyses from the Surveillance, Epidemiology, and End Results (SEER) Program.
7,9,10) Survival has not been shown to be dependent on whether the primary cancer
in the mastectomy specimen was found or not.
The MA 17 trial included 889 women who were premenopausal and 4,277 who were postmenopausal at the time of their primary cancer
Cancer survivors, particularly survivors of childhood cancer, are at increased risk not only for the recurrence of the primary cancer
but also for the development of second primary malignancies in a new site or tissue.
While authors primarily focus on primary cancer
prevention--as in before it actually happens, there is also a chapter on secondary prevention (finding cancer and preventing it from spreading) and some notes on tertiary prevention (support methods for individuals with cancer).
Census region, and primary cancer
site/leading diagnosis, using the most recent data available from the National Vital Statistics System (NVSS).
BRCA1 and BRCA2 increase the risk of breast (50-85%) and ovarian cancer (16-50%) and identifying these mutations in women with breast cancer is important as the risk of a second primary cancer
or new ovarian cancer is high.
While some subsequent tumors are recurrences of the primary cancer
, many are new tumors biologically unrelated to the first one.
Outcome measures were all-cause and cancer mortality, disease-free survival, cancer recurrence, second primary cancer
, recurrence of a preinvasive lesion or progression to cancer.
Since the tongue is a rare metastatic site, when a lesion is detected, a thorough evaluation to distinguish between metastasis or primary cancer
should be made.