synaptic vesicle

(redirected from Presynaptic vesicle)
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Related to Presynaptic vesicle: synaptic cleft, synaptic gap

synaptic vesicle

n.
Any of several small, intracellular, membrane-bound vesicles at a synaptic junction of neurons that contain a neurotransmitter.

synaptic vesicle

A membranous sac located within the presynaptic membrane of an axon terminal and containing a neurotransmitter.
See also: vesicle
References in periodicals archive ?
Many immunohistochemical markers are used in diagnosis of neuroendocrine tumors: enzymes (neuron specific enolase, NSE); proteins stored in the secretory granules (chromogranin A and HISL- 19 protein); resident proteins of the presynaptic vesicles; proteins of the cytoskeleton (neurofilament); catecholamines and indolamines (epinephrine, norepinephrine, dopamine, serotonine); neuropeptides (enkephaline, VIP, corticotropine); molecules with unknown functions (PGP 9.5, myelin associated glycoprotein Leu-7).
The neurotransmitter molecules released from the presynaptic vesicles traverse the synaptic gap and bind to proteins, termed neurotransmitter receptors, on the surface membrane of the postsynaptic neuron.
Literature evidences suggest that presynaptic kinases regulate neurotransmitter release, mainly affecting three steps: stored vesicle mobilization [66], axonal ending depolarization due to calcium influx [67], and presynaptic vesicles fusion [68].
The presynaptic vesicles were aligned at the presynaptic membrane opposite a series of cross filaments in the synaptic cleft and a postsynaptic density (Fig.