PSA

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PSA

Abbreviation for prostate-specific antigen.

PSA

abbr.
1. prostate-specific antigen
2. public service announcement

PSA

Prostate-specific antigen. A 34-kD glycoprotein serine protease (formally, kallikrein-related peptidase 3) encoded by KLK3 on chromosome 19q13.41, which has significant homology with other neutral proteases. It is secreted exclusively by the prostate epithelium and is responsible for lysing the seminal coagulum; it is present in the serum and is increased in patients with both benign (acute inflammation and BPH) and malignant (cancer) prostate lesions;. Most serum PSA is bound to protease inhibitors, including alpha1-antichymotrypin (the form usually measured in the lab), alpha1-macroglobulin, and in far lower amounts to alpha1-antitrypsin; small amounts of PSA in the circulation are not bound—i.e., free—to a carrier protein. Prostate cancer is present in 22% of those with PSA levels above 4.0 µg/L, and 60% of those with levels above 10 µg/L.

PSA

Prostate-specific antigen Urology A 34 kD glycoprotein serine protease with significant homology with other neutral proteases; PSA is secreted exclusively by the prostate epithelium and is responsible for lysing the seminal coagulum; it is present in the serum and is ↑ in Pts with both benign–acute inflammation and BPH and malignant–CA prostate lesions; most serum PSA is bound to protease inhibitors, including α1-antichymotrypin–the form usually measured in the lab, α1-macroglobulin, and in far lower amounts to α1-antitrypsin; small amounts of PSA in the circulation are not bound–ie, free—to a carrier protein; prostate CA is present in 22% of those with PSA levels above 4.0 µg/L, 60% of those with levels above 10 µg/L

PSA

Abbreviation for prostate-specific antigen.

PSA

See PROSTATE-SPECIFIC ANTIGEN.

PSA (Prostate specific antigen)

A tumor marker associated with prostate cancer.
Mentioned in: Tumor Markers

Patient discussion about PSA

Q. Would kidney stones affect a PSA reading? Would drinking lots of grapefruit juice affect a PSA reading? My husband's PSA reading jumped from a 4.2 to a 17 in @ 2 years' time. How can that be? This man takes all sorts of supplements and really watches his diet. He also takes good care of his body, and does NOT look or act 68.

A. You should get your parathyroid gland checked out. Your calcium level might be causing the kidney stones.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.
Source: http://www.northshore.org/healthresources/encyclopedia/encyclopedia.aspx?Version=Q3_08&DocumentHwid=hw5522&ViewHwid=hw5548

More discussions about PSA
References in periodicals archive ?
* laminating the pressure-sensitive adhesive tape to the polypropylene film to achieve maximum bond strength.
Novamelt is a leading manufacturer of environmentally friendly, pressure-sensitive adhesives and 100% solid PSA, which are sold under the Novamelt PS and Novamelt RC brands.
The bond formed by a pressure-sensitive adhesive cannot be explained by the reasoning above.
Pressure-Sensitive Adhesive Fabric Tape For Wire Harness Bundling: No.
The adhesive areas on the wings cannot contact the adhes ive areas on the backing sheet without an undergarment in place and with any release from the removed, the adhesive areas on the wings is offset from the adhesive areas on the backing sheet by an area that Is non-tacky at room temperature and comprises a first layer of pressure-sensitive adhesive. On top of the first layer, there is a layer of non-pressure sensitive hot melt adhesive that is non-tacky at room temperature.
Several personnel appointments have been made by Adhesives Research, Glen Rock, PA, a global developer and manufacturer of high-performance, specialty pressure-sensitive adhesive systems.
Patented is a pressure-sensitive adhesive tape closure system with a closure tape laminate made of a fastening tape tab portion with two substrates, one of which has two faces and a release tape tab portion, and the other of which has two faces.
This has opened the door for pressure-sensitive adhesives (PSAs) to gain in popularity as a safe, reliable and cost-effective alternative.
The release liners are coated with 3M's fluoropolymer, designed to provide ease of release from skin contact adhesives, including silicone, acrylates, polyisobutylene (PIB) and rubber based pressure-sensitive adhesives. The liners also provide chemical stability for a long shelf life.
[USPRwire, Mon Nov 17 2014] Pressure-sensitive adhesives are a category of adhesives that form a bond with the substrate on the application of slight pressure.
Henkel offers an extensive range of pressure-sensitive adhesives for self-adhesive labels and laminations.
* Availability with or without pressure-sensitive adhesives.

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