Betal nut chewing is the most popular chewing habit in among South Asians.12 According to an estimate of World Health Organization (WHO) approximately 600 million people chew betal nut containing products worldwide which is about 10-20% of the world's population causing a premalignant condition
of oral cavity known as oral submucous fibrosis (OSF).13 Research has shown that betal nut is the fruit of areca catechu palm tree and is chewed for its mild central nervous system stimulating properties.
"Once you see that the treatment is safe and the results are consistent, there's no reason why it shouldn't be used to treat Barrett's, which we know is a premalignant condition
," he said.
INTRODUCTION: Oral submucous fibrosis (OSF) is a well-known premalignant condition
which is insidious and progressive affecting the entire oral cavity, sometimes even extends to the pharynx.
PIN is generally considered to be a premalignant condition
, because 80% of patients with prostate cancer also have histologic evidence of PIN.
As lichen planus is known to be a premalignant condition
, its common occurrence in a population group highlights the importance of getting more and more familiar with its different patterns so that these lesions are picked up early in their course and appropriate management is instituted.
Overall squamous intraepithelial lesions were found in 10.5% of rural areas and 4.5% of the urban area subjects, it indicates significantly higher incidence of premalignant condition
of cervical cancer among rural population than among the urban population.
Actinic keratosis is a premalignant condition
. The lesion starts as flat scaly areas and later grows into a large wart like lesions.
During the exam, the physician checks for malignancy or premalignant conditions
while evaluating the quality of the vaginal and vulvar tissue.
The conditions relating to premalignant conditions
of endometrium are graded as hyperplasia.
Most strikingly, 6 (1%) specimens were from patients with premalignant conditions
, that is, intestinal metaplasia, and gastric adenocarcinoma was identified in 1 (0.17%) specimen (Table 1).
Endometrial biopsy should be performed in all women over 40 years of age who presents with AUB to rule out premalignant conditions
or endometrial carcinoma.
It is one of the most prevalent premalignant conditions
across South Asia.2 Progressive fibrosis of the oral soft tissues results in limited mouth opening and diminished oral function.