Prelingual hearing impairment | definition of Prelingual hearing impairment by Medical dictionary
prelingual deafness (redirected from Prelingual hearing impairment)
hearing impairment occurring before development of speech and language skills.Hearing loss that precedes the onset of speech or learning spoken language; it is severe, stable, and less common than post-lingual hearing loss.
Aetiology Prelingual hearing loss is largely inherited: 50% are monogenic, 75% are autosomal recessive; 20%, autosomal dominant; 5%, X-linked recessive; the rest are caused by perinatal factors, infections in infancy or trauma
Hearing impairment that is present in infancy and childhood, before language skills are acquired.
References in periodicals archive
Mutations in TMPRSS3 have previously been described to cause autosomal recessive progressive hearing impairment with postlingual onset (DFNB8) as well as severe-to-profound prelingual hearing impairment
 Up to 75% of prelingual hearing impairment
has some genetic origin.
In autosomal recessive, the first locus DFNB1 (Cx26 gene) was identified in two Tunisian consanguineous families with bilateral profound prelingual hearing impairment