preimplantation genetic diagnosis

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preimplantation genetic diagnosis (PGD)

in assisted reproductive technology, the determination of chromosomal abnormalities in the embryo before it is transferred to the uterus.

preimplantation genetic diagnosis

In assisted reproduction, the testing of a fertilized egg for heritable illnesses before the ovum is inserted into the female.
See also: diagnosis

preimplantation genetic diagnosis

The use of genetic analysis in the course of vitro fertilization to ensure that a baby does not possess a known genetic defect of either parent. After analysis of the embryos formed, only those free of defect are implanted in the mother's womb. A new method, developed in 2006, involves taking a single cell from the IVF embryo, amplifying the entire genome to provide many copies, and then comparing the chromosome containing the known family mutation with those of other family members by standard DNA fingerprinting techniques.
References in periodicals archive ?
Pre-implantation genetic diagnosis enabled her and her husband to have children that they wouldn't have otherwise.
This technique allows couples to se in vitro fertilisation (IVF) with pre-implantation genetic diagnosis to identify embryos that are an HLA match and only use those embryos to establish pregnancy," he added.
HOW IT'S DONE PRE-IMPLANTATION genetic diagnosis, or PGD, is IVF treatment with a twist.
The procedures sought included sperm donation, ICSI with ejaculated or donated sperm, ICSI with non-ejaculated sperm, IVF with own gametes or donated gametes, and pre-implantation genetic diagnosis.
The use of pre-implantation genetic diagnosis is currently allowed in Australia only in cases where parents suffer serious genetic diseases that can be passed to children of one gender.
What we see with pre-implantation genetic diagnosis is simply the next high-tech preventative measure.
The technique, known as pre-implantation genetic diagnosis (PGD) has already been used in the UK to free babies of inherited disorders such as cystic fibrosis and Huntington's disease.
Second, to standardize the method in the laboratory so that laboratory is equipped to offer pre-implantation genetic diagnosis (PGD) in future as and when requirement arises.
In 13 chapters, international contributors describe analytical techniques for those providing care for couples seeking treatment for infertility or pre-implantation genetic diagnosis, and other clinical and research scientists seeking to glean diagnostic information from a minimal number of cells.
A new survey of in-vitro fertilization clinics revealed that some deaf people have been using pre-implantation genetic diagnosis to make sure that their children will be deaf.
A technique already exists - pre-implantation genetic diagnosis, in which a single cell is extracted from an embryo for genetic analysis - which shows that embryos can regularly survive such a procedure.
The technique is used in pre-implantation genetic diagnosis to determine which embryos to terminate, and scientists would do better to seek other ways to create stem cells, said Edward J.