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Related to povidone-iodine: Betadine


a synthetic polymer used as a dispersing and suspending agent. Called also polyvinylpyrrolidone.
povidone-iodine (PVP-I) a complex produced by reacting iodine with the polymer povidone; it slowly releases iodine and is used as a topical antiinfective agent.

po·vi·done i·o·dine

a water soluble complex of iodine with polyvinylpyrrolidone. Applied as an antiseptic in the form of solutions or ointments, it releases iodine. Used in cleansing and disinfecting the skin, preparing the skin preoperatively, and treating infections susceptible to iodine.


[pō′vidōn ī′ədīn]
an antiseptic microbicide.
indications It is prescribed as a topical microbicide for disinfection of wounds, as a preoperative surgical scrub, for vaginal infections, and for antiseptic treatment of burns. A drop is also often placed into the eyes of neonates to prevent ophthalmia neonatorum.
contraindications Known hypersensitivity to this drug or to iodine prohibits its use.
adverse effects Among the more serious adverse effects are local skin irritation, redness, and swelling.


An antiseptic drug suitable for application to the skin or, in the form of pessaries, to the vagina. It is also used as a mouthwash or gargle to treat mouth infections. Brand names are Betadine and Inadine.


turning inward


a complex produced by reacting iodine with the polymer povidone; used as a topical anti-infective. Called also Betadine.
References in periodicals archive ?
The average cost per patient for the MRSA screening was US$11 (SD, 0), and the average cost per patient for the hand-made povidone-iodine nasal swabs was US$1 (SD, 0; Table 3).
diadematus and honey treated mice runs parallel to the synthetic povidone-iodine in compensating the skin damage and antiseptic properties.
Of the 50 patients with otorrhea, 50 (100%) were treated with topical antibiotics, 30 (60%) were treated with oral antibiotics, and 12 (24%) received povidone-iodine irrigation.
Keywords: Adenoviral conjunctivitis, Povidone-iodine, pH.
Compared with patients in the povidone-iodine group, those in the chlorhexidine-alcohol group had several medical comorbidities, demographic and perioperative factors associated with the development of SSIs, including being more likely to have a BMI of 30 kg/m2 or greater; American Society of Anesthesiology Class of 3 or greater; dependent functional status; malignancy as a preoperative indication for surgery; estimated blood loss of greater than 250 cc; and surgery lasting longer than 3 hours.
The usefulness of povidone-iodine on intact skin is well-established5,6 but its use as a prophylactic irrigation solution against surgical site infection (SSI) is limitedly addressed7,8.
At this time, there is a paucity of current evidence comparing povidone-iodine to chlorhexidine gluconate.
However Chlorhexidine-alcohol was significantly more protective than povidone-iodine against both superficial incisional infections and deep incisional infections but not against organ-space infections.
On the basis of the study findings, the estimated number of patients who would need to undergo skin preparation with chlorhexidine-alcohol instead of povidone-iodine in order to prevent one case of surgical-site infection is approximately 17.
In this study, loading of Povidone-iodine was performed by allowing the dry hydrogels to swell in the Povidone-iodine solution of known concentration and then taking out and drying them at room temperature.
Garglers were asked to use 20 mL of water or diluted povidone-iodine for about 15 seconds three times consecutively, and to repeat this protocol at least three times daily They were followed for at least 60 days.
25% solution of povidone-iodine proved as effective for treating bacterial and chlamydial conjunctivitis as neomycin-polymyxin B-gramicidin ophthalmic solution.