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tuberculosis of the spine, usually beginning as a tuberculous osteomyelitis of the vertebrae and progressing to damage of the intervertebral disks. If erosion continues unchecked, there is complete destruction of the affected vertebrae. Symptoms include stiffness of the back, pain on motion, prominence of the spinous process of certain vertebrae, and occasionally abscess formation, paralysis, and abdominal pain. Diagnosis is confirmed by demonstration of Mycobacterium tuberculosis in the affected bone. Treatment includes administration of antibacterial drugs such as isoniazid and streptomycin. Para-aminosalicylic acid (PAS) may be used instead of streptomycin if streptomycin is contraindicated. Surgical fixation of the affected vertebrae (spinal fusion) may be required for correction of orthopedic deformities such as kyphosis that may occur as a result of Pott's disease.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Tuberculosis of the spine, leading, if untreated, to destruction of the vertebral bones, curvature of the spine, and paraplegia.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Pott's diseaseTuberculosis of the spine, with collapse of one or more vertebrae, so as to produce a sharp angulation and a hump-back. Also known as spinal caries. (Sir Percivall Pott, 1714–88, English surgeon).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005