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tuberculosis of the spine, usually beginning as a tuberculous osteomyelitis of the vertebrae and progressing to damage of the intervertebral disks. If erosion continues unchecked, there is complete destruction of the affected vertebrae. Symptoms include stiffness of the back, pain on motion, prominence of the spinous process of certain vertebrae, and occasionally abscess formation, paralysis, and abdominal pain. Diagnosis is confirmed by demonstration of Mycobacterium tuberculosis in the affected bone. Treatment includes administration of antibacterial drugs such as isoniazid and streptomycin. Para-aminosalicylic acid (PAS) may be used instead of streptomycin if streptomycin is contraindicated. Surgical fixation of the affected vertebrae (spinal fusion) may be required for correction of orthopedic deformities such as kyphosis that may occur as a result of Pott's disease.
Tuberculosis of the spine, leading, if untreated, to destruction of the vertebral bones, curvature of the spine, and paraplegia.