potassium-sparing diuretic

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potassium-sparing diuretic

Medtalk A diuretic that effects mild diuresis, while conserving K+ and Mg2+; PSDs may be more effective in maintaining the electrolyte balance than cation–K+, magnesium supplementation; PSDs include amiloride, triameterene, diazide, maxide, spironolactone See Diuretics. Cf Loop diuretic.

potassium-sparing diuretic

An agent that stimulates the kidneys to excrete water and sodium while retaining potassium. Drugs from this therapeutic class are used to treat hypertension, fluid retention in cirrhosis, and congestive heart failure.
See also: diuretic
References in periodicals archive ?
Potassium-sparing diuretics inhibit sodium reabsorption in the latter parts of the distal tubule and the early collecting duct (Figure 3, F).
Note: Some diseases (like heart failure or kidney disease) and some drugs (like ACE inhibitors, angiotensin II receptor blockers, and potassium-sparing diuretics) make it hard to excrete potassium.
Some patients may require medications such as potassium-sparing diuretics such as spironolactone or amiloride.
While rare, this condition can occur in people who have chronic kidney disease and those who use angiotensin converting enzyme (ACE) inhibitors and potassium-sparing diuretics.
This effect is similar to the effect seen with the potassium-sparing diuretic amiloride.
Additional results of this study, particularly the increase in serum potassium and decreases in systolic and diastolic blood pressure, are promising and suggest that future research on this dietary supplement, or its ingredients, should further explore effects on blood pressure and biologic mechanisms of action, which may involve potassium-sparing and diuretic effects.
And if you take certain medications such as ACE inhibitors and potassium-sparing diuretics, talk to your doctor.
Exclusion criteria included poor renal function (glomerular filtration rate less than 60 ml per minute) and the use of potassium-sparing medicines.
For potassium-sparing diuretics, the evidence is even more scarce, with no interaction in most studies and small increases in lithium levels on other studies, apparently being amiloride the safest option in the class.
In this regard, potassium-sparing diuretic eplerenone maybe preferable to prevent hypokalemia.
Potassium-sparing diuretics conserve potassium by inhibiting the action of aldosterone.