diuretics conserve potassium by inhibiting the action of aldosterone.
diuretics, such as amiloride, spironolactone (Aldactone), and triamterene (Dyrenium).
The approval marks the first and only FDA-approved oral liquid dosage form of the potassium-sparing
If the target BP cannot be achieved with 3 drugs in those classes, other medications such as potassium-sparing
diuretics or beta-blockers can be added.
Pharmaceutical company CMP Pharma reported on Monday the receipt of final approval from the US Food and Drug Administration (FDA) for its New Drug Application (NDA) for CaroSpir, which is the first and only US FDA-approved oral liquid dosage form of the potassium-sparing
Hyperkalemia is also a potential concern if salt substitutes are used with certain blood pressure medications that cause your body to retain potassium, such as angiotensin-converting enzyme (ACE) inhibitors--benazepril (Lotensin[R]), enalapril (Vasotec[R]), lisinopril (Prinivil[R], Zestril[R]), and quinapril (Accupril[R]) are examples--and potassium-sparing
diuretics--amiloride (Midamor[R]), eplerenone (Inspra[R]), spironolactone (Aldactone[R]), and triamterene (Dyrenium[R]).
These drugs include alpha-2 receptor agonists and loop diuretics, potassium-sparing
diuretics, thiazide diuretics, and combination diuretics, Katherine Levandoski said at the annual meeting of the Society for Investigative Dermatology.
Common medications that can drive up potassium include ACE inhibitors, potassium-sparing
diuretics, and beta blockers.
diuretics such as amiloride have been avoided because of perceived lack of BP-lowering efficacy and increased risk of hyperkalemia because of increasing use of RAS blockers.
There are different types of diuretics, including thiazide, loop and potassium-sparing
Amiloride, which is a potassium-sparing
diuretic that acts as a direct antagonist of the epithelial sodium channel (ENaC) in the distal convoluted tubules, has also been successfully used in pregnancy without report of any adverse outcomes .
I believe these results will return potassium-sparing
diuretics to prominence," said Dr.