diuretics inhibit sodium reabsorption in the latter parts of the distal tubule and the early collecting duct (Figure 3, F).
Note: Some diseases (like heart failure or kidney disease) and some drugs (like ACE inhibitors, angiotensin II receptor blockers, and potassium-sparing
diuretics) make it hard to excrete potassium.
Some patients may require medications such as potassium-sparing
diuretics such as spironolactone or amiloride.
While rare, this condition can occur in people who have chronic kidney disease and those who use angiotensin converting enzyme (ACE) inhibitors and potassium-sparing
This effect is similar to the effect seen with the potassium-sparing
Ratios >10.0 indicate a potassium-sparing
Additional results of this study, particularly the increase in serum potassium and decreases in systolic and diastolic blood pressure, are promising and suggest that future research on this dietary supplement, or its ingredients, should further explore effects on blood pressure and biologic mechanisms of action, which may involve potassium-sparing
and diuretic effects.
And if you take certain medications such as ACE inhibitors and potassium-sparing
diuretics, talk to your doctor.
Exclusion criteria included poor renal function (glomerular filtration rate less than 60 ml per minute) and the use of potassium-sparing
diuretics, the evidence is even more scarce, with no interaction in most studies and small increases in lithium levels on other studies, apparently being amiloride the safest option in the class.
In this regard, potassium-sparing
diuretic eplerenone maybe preferable to prevent hypokalemia.
diuretics conserve potassium by inhibiting the action of aldosterone.