potassium-sparing diuretic

(redirected from Potassium-sparing)

potassium-sparing diuretic

See diuretic.

potassium-sparing diuretic

Medtalk A diuretic that effects mild diuresis, while conserving K+ and Mg2+; PSDs may be more effective in maintaining the electrolyte balance than cation–K+, magnesium supplementation; PSDs include amiloride, triameterene, diazide, maxide, spironolactone See Diuretics. Cf Loop diuretic.

potassium-sparing diuretic

An agent that stimulates the kidneys to excrete water and sodium while retaining potassium. Drugs from this therapeutic class are used to treat hypertension, fluid retention in cirrhosis, and congestive heart failure.
See also: diuretic
References in periodicals archive ?
Potassium-sparing diuretics conserve potassium by inhibiting the action of aldosterone.
Potassium-sparing diuretics, such as amiloride, spironolactone (Aldactone), and triamterene (Dyrenium).
The approval marks the first and only FDA-approved oral liquid dosage form of the potassium-sparing diuretic spironolactone.
If the target BP cannot be achieved with 3 drugs in those classes, other medications such as potassium-sparing diuretics or beta-blockers can be added.
Pharmaceutical company CMP Pharma reported on Monday the receipt of final approval from the US Food and Drug Administration (FDA) for its New Drug Application (NDA) for CaroSpir, which is the first and only US FDA-approved oral liquid dosage form of the potassium-sparing diuretic spironolactone.
Hyperkalemia is also a potential concern if salt substitutes are used with certain blood pressure medications that cause your body to retain potassium, such as angiotensin-converting enzyme (ACE) inhibitors--benazepril (Lotensin[R]), enalapril (Vasotec[R]), lisinopril (Prinivil[R], Zestril[R]), and quinapril (Accupril[R]) are examples--and potassium-sparing diuretics--amiloride (Midamor[R]), eplerenone (Inspra[R]), spironolactone (Aldactone[R]), and triamterene (Dyrenium[R]).
These drugs include alpha-2 receptor agonists and loop diuretics, potassium-sparing diuretics, thiazide diuretics, and combination diuretics, Katherine Levandoski said at the annual meeting of the Society for Investigative Dermatology.
Common medications that can drive up potassium include ACE inhibitors, potassium-sparing diuretics, and beta blockers.
Potassium-sparing diuretics such as amiloride have been avoided because of perceived lack of BP-lowering efficacy and increased risk of hyperkalemia because of increasing use of RAS blockers.
There are different types of diuretics, including thiazide, loop and potassium-sparing diuretics.
Amiloride, which is a potassium-sparing diuretic that acts as a direct antagonist of the epithelial sodium channel (ENaC) in the distal convoluted tubules, has also been successfully used in pregnancy without report of any adverse outcomes [16].
I believe these results will return potassium-sparing diuretics to prominence," said Dr.