DLG4

(redirected from Postsynaptic density protein 95)

DLG4

A gene on chromosome 17p13.1 that encodes a member of the membrane-associated guanylate kinase (MAGUK) family that forms a complex with another MAGUK, DLG2, and is recruited into NMDA receptor and potassium channel clusters. DLG2 and DLG4 may interact at postsynaptic sites to form a multimeric scaffold for clustering of receptors, ion channels and signalling proteins.
References in periodicals archive ?
Taken from a structural point of view, it is important to emphasize that oxytocin receptor knockout mice suffer from reduction of postsynaptic density protein 95 [69].
The postsynaptic density protein 95 (PSD-95; also known as DLG4 and SAP90) is the most abundant protein in excitatory chemical synapses and the main scaffolding protein at the PSD.