Negative symptoms were more closely associated with the occupational functioning measures than positive symptoms
, a finding that is consistent with previous reports that find improvements in the negative symptoms of patients who participate in occupational skills-training programs.
* dopaminergic hyperactivity in mesolimbic dopaminergic pathways contributes to positive symptoms
of schizophrenia--hallucinations, delusions, disorganized thoughts and behaviors, and catatonia
To more closely examine the drug's efficacy in domains other than positive symptoms
such as delusions and hallucinations, Dr.
Current antipsychotics are reasonably effective in treating positive symptoms
, but they do less to improve the negative and cognitive symptoms (1) that contribute to patients' long-term poor functional capacity and quality of life.
The investigators found that FH and sex interacted to influence the severity of negative symptoms, but not positive symptoms
(hallucinations, delusions, thought disorder, etc.) and--to a lesser extent--negative symptoms (anhedonia, asociality, blunted affect, etc.) often improve when patients are treated with antipsychotics.
seemed to fade away over time and were less prominent [by 20 years' follow-up] in all groups," Dr.
* result in positive symptoms
, such as ideas of reference or paranoid delusions, when the individual with schizophrenia misperceives ordinary social cues as "threats."
Usall and her colleagues found that adding 60 mg daily of raloxifene--the standard dosage indicated for osteoporosis prevention--to regular antipsychotic treatment improved psychotic symptoms at 12 weeks, compared with antipsychotics alone, with reduction in negative symptoms, (P = .044), positive symptoms
(P = .031), and general psychopathological symptoms (P = .045), and without significant adverse effects (J.
Specially adapted cognitive therapy improved global function, motivation, and positive symptoms
in low-functioning patients who had chronic schizophrenia and significant cognitive impairment, according to a study in the journal.
The mean scores on the shortened SUMD were 4.81 for awareness of their mental disorder, 3.42 for level of awareness of positive symptoms
, and 3.79 for level of awareness of negative symptoms.
In addition, women tend to present more positive symptoms
than do men - symptoms that have been linked to suicide risks.