A non-motile, gram-negative, anaerobic bacillus of the phylum Bacteroidetes, which forms black colonies on blood agar. It is found in the oral cavity, where it causes periodontal disease by producing collagenase, and has been cultured from gastrointestinal and respiratory tract specimens and from patients with rheumatoid arthritis.
The quantification of Porphyromonas gingivalis (Pg), Aggregatibacter actinomycetemcomitans (Aa), Tannerella forsythia (Tf) and Treponema denticola (Td) was made by real-time PCR in a StepOnePLus TM thermocycler (Applied Biosystems[R], Foster City, CA, USA), using specific primers.
3] Tannerela forsythia, Porphyromonas gingivalis, Treponema denticola, and Aggregatibacter actinomycetemcomitans found within the peri-implant sulcus were related to the peri-implant crevicular fluid volume.
Blackberry extract significantly reduced the metabolic activity of three key oral bacteria: Porphyromonas gingivalis and Fusobacterium nucleatum (both known to cause periodontal disease) by 40%, and Streptococcus mutans (responsible for dental caries) by 30%.