porphyrin


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porphyrin

 [por´fĭ-rin]
any of a group of iron- or magnesium-free cyclic tetrapyrrole derivatives, occurring universally in protoplasm, and forming the basis of the respiratory pigments of animals and plants; in combination with iron they form hemes. Examples include coproporphyrin, hematoporphyrin, protoporphyrin, and uroporphyrin. See also porphyria.

por·phin

, porphine (pōr'fin),
The unsubstituted cyclic tetrapyrrole nucleus that is the basis of the porphyrins.
See also: porphyrins. Compare: chlorin, phorbin, corrin.
Synonym(s): porphyrin

porphyrin

/por·phy·rin/ (por´fĭ-rin) any of a group of compounds containing the porphin structure to which a variety of side chains are attached, the nature of the side chain indicated by a prefix; they occur in the prosthetic groups of hemoglobins, myoglobin, and cytochromes, complexed with metal ions, and occur free in tissues in porphyrias. The term is sometimes used to include or to denote porphin specifically.
Enlarge picture
Porphyrin. (A), Pyrrole ring; (B), porphin ring; (C), protoporphyrin IX.

porphyrin

(pôr′fə-rĭn)
n.
Any of various organic compounds containing four pyrrole rings, occurring universally in protoplasm, and functioning as a metal-binding cofactor in hemoglobin, chlorophyll, and certain enzymes.

porphyrin

[pôr′fərin]
Etymology: Gk, porphyros, purple
any iron- or magnesium-free pyrrole derivative occurring in many plant and animal tissues. Normal findings of porphyrins in urine are 50 to 300 mg/24 hours.

porphyrin

an organic compound consisting of four pyrrole rings linked by CH bridges with a heavy metal in the centre. Porphyrins form part of several important biological molecules. Examples include the haem group of HAEMOGLOBIN and MYOGLOBIN (see Fig. 258 ), chlorophyll (with magnesium) and cytochromes (with iron).

Porphyrin

A type of pigment found in living things, such as chlorophyll, that makes plants green and hemoglobin which makes blood red.

porphyrin

any of a group of iron- or magnesium-free cyclic tetrapyrrole derivatives which forms the basis of the respiratory pigments of animals and plants. Porphyrins, in combination with iron, form hemes.

porphyrin test
the presence of porphyrin in cultures of Hemophilus spp. or Tayorella equigenitalis indicates that hemin is not required for growth.
References in periodicals archive ?
Temporal investigation of phase conjugation, with enhancement, in magnesium tetraphenyl porphyrin.
KEY WORDS: Na+, K+-ATPase, Porphyrin derivatives, Diabetes Mellitus, Acetylcholinesterase, Dysnatremias.
Biochemistry is typical of PCT: raised urine porphyrins (predominantly uro- and heptacarboxylic porphyrins) with normal PBG and increased stool porphyrins showing a series of decarboxylated intermediates and the characteristic isocoproporphyrin (8).
In the other structures, the copper is slightly displaced out of the porphyrin plane, depending on the strength of the axial bonds; these displacements are, however, generally very small, cf.
78% V (IV) octa-etioporphyrin (VOHDM-OEP) using commercial porphyrins by electrochemical techniques.
The collapse of the epithelial cell layer resulting from HpD treatment resembles that observed with the histopathological effects of novel, meso-substituted cationic porphyrin (Lucatoni et al.
The authors thank Brandon Davidson and Maglona Paul for performing the porphyrin biochemistry and DNA extraction.
Borylated porphyrins are quite useful building blocks for the synthesis of novel and exotic porphyrin derivatives, (15) which are otherwise difficult to access by the conventional porphyrin synthesis.
The main theme of the Symposium is "Innovative Research on 5-Aminolevulinic Acid (ALA) and Porphyrin Metabolism & Clinical Applications such as diagnosis and treatment of cancer".
Modeling the haloperoxidases: Reversible oxygen atom transfer between bromide ion and an oxo-Mn(V) porphyrin.
Thus laboratory testing based on the definite pattern of accumulation and hyper-excretion of porphyrins and porphyrin precursor is most effective for diagnosis and typing of porphyrias.
The current grouping of the porphyrias is based on the primary site of increased porphyrin production, either liver or bone marrow-the hepatic or erythropoietic porphyrias, respectively.