polysorbates


Also found in: Dictionary, Encyclopedia.

polysorbates

(pŏl″ē-sor′bāts)
Nonionic surface-active agents composed of polyoxyethylene esters of sorbitol. They usually contain associated fatty acids. The series includes polysorbates 20, 40, 60, and 80, which are used in preparing pharmaceuticals. These polysorbates have the trade names of Tween 20, Tween 40, and so forth.
References in periodicals archive ?
Polysorbate damage to biotherapeutics is discussed at length in a just published review article in the Journal of Excipients and Food Chemicals.
Polysorbate 60 and its close relatives, polysorbate 65 and polysorbate 80, work like mono- and diglycerides.
Key advantages of these products will be: all-natural, no preservatives (such as potassium sorbate or EDTA), no undeclared additives and only GRAS, clean label ingredients for direct food use (no polysorbates or hydrogenated castor oil PEG 40).
A universal-detection method for pharmaceutical manufacturing operations uses reverse-phase HPLC with the Corona CAD de tector for sensitive and robust analysis of polysorbates.
There is no need for EDTA or preservatives, there are no detergents or polysorbates.