polyene

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polyene

 [pol´e-ēn]
1. a chemical compound with a carbon chain of four or more atoms and several conjugated double bonds.
2. any of a group of antibiotic antifungal agents with similar structure, such as amphotericin b, candicidin, or nystatin; they are produced by species of Streptomyces that damage cell membranes by forming complexes with sterols.

pol·y·ene

(pol'ē-ēn),
A chemical compound having a series of conjugated (alternating) double bonds; for example, the carotenoids.
References in periodicals archive ?
Thus, all properties of these compounds in table 2 are not located in definition ranges for polyene antibiotics. Based on tables 1 and 2, NSC 89270 has more similar properties to polyene macrolid antibiotics than NSC 62792.
Ergosterol is the site of interaction for polyene antibiotics while azoles interfere with ergosterol synthesis.