Polyadenosine | definition of Polyadenosine by Medical dictionary
polyadenylation (redirected from Polyadenosine)
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1. The process of formation of poly(adenylic acid).
2. The covalent modification of a macromolecule (for example, mRNA) by the formation of a polyadenylyl moiety covalently linked to the macromolecule.
polyadenylation The process by which a sequence of polyadenylic acids (adenosine ribonucleotides) is added to the end of a spliced RNA after its transcription from DNA, resulting in mature mRNA. This addition on the RNA molecule is sometimes referred to as a poly-A tail, and commonly contains several-hundred bases.
polyadenylation addition of a sequence of ADENINE NUCLEOTIDES to the 3′-end of most eukaryotic RNA molecules, after their TRANSCRIPTION. The sequence is often called a.poly(A) tail.
References in periodicals archive
Protection by thymidine, an inhibitor of polyadenosine
diphosphate ribosylation, of streptozotocin inhibition of insulin secretion.
reported that a novel VDR polymorphism defined by length of polyadenosine
residues in the 3'UTR was associated with the risk of PrCa among non-Hispanic whites.
The hybridization buffer consisted of 10% dextran, 0.2% bovine serum albumin, and 0.01% polyadenosine
, in 5X SET buffer; the 25X SET buffer consisted of 3.75M sodium chloride, 25 mM EDTA, and 0.5M Tris at pH 7.8.