polyadenylation

(redirected from Polyadenosine)
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pol·y·ad·e·nyl·a·tion

(pol'ē-ad'ĕ-nil-ā'shŭn),

1. The process of formation of poly(adenylic acid).

2. The covalent modification of a macromolecule (for example, mRNA) by the formation of a polyadenylyl moiety covalently linked to the macromolecule.

Farlex Partner Medical Dictionary © Farlex 2012

polyadenylation

The process by which a sequence of polyadenylic acids (adenosine ribonucleotides) is added to the end of a spliced RNA after its transcription from DNA, resulting in mature mRNA. This addition on the RNA molecule is sometimes referred to as a poly-A tail, and commonly contains several-hundred bases.

polyadenylation

addition of a sequence of ADENINE NUCLEOTIDES to the 3′-end of most eukaryotic RNA molecules, after their TRANSCRIPTION. The sequence is often called a.poly(A) tail.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

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reported that a novel VDR polymorphism defined by length of polyadenosine residues in the 3'UTR was associated with the risk of PrCa among non-Hispanic whites.

Vitamin D receptor gene Bsm1 polymorphism positively correlates with prostate cancer

The hybridization buffer consisted of 10% dextran, 0.2% bovine serum albumin, and 0.01% polyadenosine, in 5X SET buffer; the 25X SET buffer consisted of 3.75M sodium chloride, 25 mM EDTA, and 0.5M Tris at pH 7.8.

Rhinosporidium seeberi: A Human Pathogen from a Novel Group of Aquatic Protistan Parasites

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