Pneumocystis jiroveci pneumonia


Also found in: Dictionary, Thesaurus, Acronyms.

Pneu·mo·cys·tis jiroveci pneu·mo·ni·a (PCP),

pneumonia resulting from infection with Pneumocystis jiroveci, frequently seen in the immunologically compromised, such as people with AIDS, or those treated with steroids, the elderly, or premature or debilitated babies during their first 3 months. In AIDS patients, tissue damage is usually restricted to the pulmonary parenchyma, whereas in the infantile form of the disease the alveoli are filled with a honeycomblike or foamy network of acidophilic material, apparently not fibrin and not stainable with silver, within which the organisms, individually or in aggregates, are enmeshed; throughout the alveolar walls and pulmonary septa there is a diffuse infiltration of mononuclear inflammatory cells, chiefly plasma cells and macrophages, as well as a few lymphocytes. Patients may be only slightly febrile (or even afebrile), but are likely to be extremely weak, dyspneic, and cyanotic. This is a major cause of morbidity among patients with AIDS.
See also: Pneumocystis jiroveci.
References in periodicals archive ?
The diagnosis of Pneumocystis jiroveci pneumonia (PCP) required the compatible clinical syndrome of fever, dyspnoea and nonproductive cough, interstitial infiltrates on CXR, and clinical response to treatment.
To determine the efficacy and safety of adjunctive corticosteroid therapy in clinical Pneumocystis jiroveci pneumonia (PCP) in infants exposed to HIV infection.
Out of 102 patients, 64(62.74 %) patients had fever, 61 (59.80%) patients had diarrhea, 43(42.15%) patients had lymphadenopathy, 69(67.64%) patients had cough, 55(53.92%) patients had weight loss, and 9(8.82 %) cases had Pneumocystis jiroveci pneumonia, 34(33.33%) cases had oral candidiasis, 54(52.94%) cases had tuberculosis, 45(44.11%) patients had Herpes, subclinical hypothyroidism was seen in 14(13.72%) patients.
He was diagnosed with Mycobacterium avium complex pneumonia and Pneumocystis jiroveci pneumonia (PJP) by bronchoscopy and discharged on trimethoprim-sulfamethoxazole (tmpsmx), azithromycin, ethambutol, and rifabutin.
(2, 7) When associated with thickening of the interlobular septa it is called crazy paving and can be seen in pneumocystis jiroveci pneumonia. (7) In patients with acute symptoms as in infections, association of ground glassing with active disease is very high.
Risk factors for Pneumocystis jiroveci pneumonia (PCP) in renal transplant recipients.
Adjunctive Corticosteroids for Pneumocystis jiroveci Pneumonia in Patients with HIV Infection: Meta-Analysis of Randomised Controlled Trials.
They concluded that 20(35.05%) patients had fungal infection, 8(14.3%) patients had viral infections, 19 (33.3%) patients had bacterial infection, 2 (3.5%) patients had tuberculosis and 8(14.3%) patients had Pneumocystis jiroveci pneumonia infection5.
An outbreak of Pneumocystis jiroveci pneumonia with 1 predominant genotype among renal transplant recipients: interhuman transmission or a common environmental source?