Pneumocystis jiroveci

Also found in: Dictionary, Thesaurus, Encyclopedia.

Pneu·mo·cys·tis jiroveci

the eukaryotic microorganism responsible for interstitial pneumonia in immunocompromised patients. The exact taxonomic position remains unclear, because the organism has morphologic similarities to protozoa but shares substantial 16S ribosomal RNA and mitochondrial DNA with some species of the Ascomycetes. P. jiroveci fails to grow on fungal culture media but takes up fungal stains, and infections from it respond to antiprotozoal as well as to some antifungal drugs.
See also: Pneumocystis jiroveci pneumonia.
[G. pneuma, air, breathing, + kystis, bladder, pouch]

Pneumocystis jiroveci

a microorganism that causes pneumocystosis, a type of interstitial cell pneumonitis.

Pneu·mo·cys·tis jir·o·ve·ci

(nū'mō-sis'tis jī-rō-vē'sī)
New nomenclature for Pneumocystis carinii, the microorganism that causes interstitial plasma cell pneumonia in immunodeficient people, particularly those with AIDS.
[G. pneuma, air, breathing, + kystis, bladder, pouch]
Enlarge picture

Pneumocystis jiroveci

[Otto Jirovec, Czech parasitologist, 1910–1972]
An opportunistic fungus that causes lung infections in those with immunosuppressive diseases and conditions. It was formerly called pneumocystis carinii.
See: illustration
References in periodicals archive ?
Association between a specific Pneumocystis jiroveci dihydropteroate synthase mutation and failure of pyrimethamine/sulfadoxine prophylaxis in human immunodeficiency virus positive and negative patients.
He was treated empirically with IV trimethoprim-sulfamethoxazole, ciprofloxacin, and ticarcillin-clavulanate for presumed Pneumocystis jiroveci pneumonia and routine nosocomial pneumonia.
The diagnosis of Pneumocystis jiroveci pneumonia (PCP) required the compatible clinical syndrome of fever, dyspnoea and nonproductive cough, interstitial infiltrates on CXR, and clinical response to treatment.
Bronchoscopy, bone marrow biopsy, and lesion biopsy were nondiagnostic, with negative staining for Pneumocystis jiroveci.
Pneumocystis jiroveci pneumonia (PCP) is an important pathogen in HIV-infected infants with severe pneumonia.
Pneumocystis jiroveci in Portuguese immunocompromised patients: association of specific ITS genotypes with treatment failure, bad clinical outcome and childhood.
Cytomegalovirus pneumonitis, Pneumocystis jiroveci (carinii) pneumonia, cytomegalovirus adrenalitis, and disseminated toxoplasmosis were identified microscopically, and pulmonary cytomegalovirus was confirmed postmortem by viral culture of the lung tissue.
Second, splenectomy can increase susceptibility to infection, such as bloodstream infections with encapsulated bacteria or opportunistic infections with Campylobacter jejuni, Pneumocystis jiroveci, or Babesia spp.
While dapsone is inferior to Bactrim as prophylaxis for Pneumocystis jiroveci pneumonia (PCP), it is still a viable option.
Administer prophylaxis against Pneumocystis jiroveci pneumonia (PCP) and herpes virus infections.
Genotypes at the internal transcribed spacers of the nuclear rRNA operon of Pneumocystis jiroveci in nonimmunosuppressed infants without severe pneumonia.
Inhaled antibiotics have so far been primarily used in the setting of Cystic Fibrosis or in the prophylaxis of Pneumocystis jiroveci.