Pneumocystis carinii

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Pneumocystis carinii

former name for Pneumocystis jiroveci (q.v.).

Pneumocystis carinii

Pneumocystosis Infectious disease An opportunistic 'bug' causing pneumonia–PCP in immunocompromised hosts–eg, with AIDS, leukemia, lymphoma, organ transplants, corticosteroid therapy, cytotoxic drugs, the elderly Diagnosis GMS staining of tissues; P carinii also causes otic infection and choroiditis Prophylaxis In advanced HIV infection, aerosolized pentamidine, T-S, and high-dose dapsone are equally effective; the latter 2 are superior in Pts with < 100 CD4+/mm3 Treatment T-S, manipulation of inflammatory response, and immune enhancement pentamidine, atovaquone, trimetrexate glucuronate

Pneu·mo·cys·tis ca·rin·i·i

(PC) (nū-mō-siśtis kă-rī-nē-ī)
Former name for Pneumocystis jiroveci (q.v.).


a genus of organisms of uncertain status, but considered to be protozoa.

Pneumocystis carinii
the causative agent of interstitial plasma cell pneumonia in humans and immunocompromised Arab foals and dogs.
References in periodicals archive ?
Pneumocystis carinii pneumonia in critically ill patients with malignancy: a descriptive study.
Mechanical ventilation for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome.
Pneumocystis carinii pneumonia: Spectrum of parenchymal CT findings.
The most frequent was the combination of tuberculosis with CMV infection (two patients) and Pneumocystis carinii pneumonia with CMV infection (one patient).
Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in immunocompromised patients.
Medications used for treatment side effects Medication Indication Leuprolide Amenorrhea Mesna Bladder toxicity and cancers from cyclophosphamide irritation Nystatin Oral and fungal infections Histamine-2 receptor antagonists Gastritis that can occur with and proton-pump inhibitors high-dose steroids Vitamin D, calcium, and Osteoporosis with chronic steroid bisphosphonates use Sulfamethoxazole and trimethoprim Pneumocystis carinii pneumonia prophylaxis
It was approved in March 1987 for persons with CD4+ cell counts of less than 200 or persons with a documented case of Pneumocystis carinii pneumonia (PCP).
The earlier identification of HIV-infected women, the use of AZT during pregnancy to prevent newborn infection, the use of prophylaxis to decrease the rate of bacterial and Pneumocystis carinii infections, and the development of more effective antiretroviral medications--all of these scientific advances have had a substantial effect on the lives of HIV-infected families and children.
The man was suffering from a rare kind of pneumonia caused by Pneumocystis carinii, a germ that ordinarily bothers only people with severely weakened immune systems.
DB-289, slated to enter human trials in the third quarter of 2000, is being developed to combat Pneumocystis carinii pneumonia (PCP), a specialized fungus that is life threatening for immune-suppressed people with cancer, organ transplants and HIV.
Other reported pathogens are mycobacteria, fungi, Pneumocystis carinii, Escherichia coli, and Salmonella typhimurium.